• Antibiotic manufacture, as well as its use, contributes to antibiotic residues in the environment, which leads to development of resistant bacteria • In South East Asia, wastewater containing antibiotics is often directly released into the environment without sufficient treatment • Research must focus on developing efficient, affordable, small scale treatment plants to eliminate antibiotic re...

BACKGROUND Antibiotic homogeneity is thought to drive resistance but in vivo data are lacking. In this study, we determined the impact of antibiotic homogeneity per se, and of cefepime versus antipseudomonal penicillin/β-lactamase inhibitor combinations (APP-β), on the likelihood of infection or colonisation with antibiotic resistant bacteria and/or two commonly resistant nosocomial pathogens (...

pseudomonas aeruginosa is one of the most important pathogens that causes nosocomial infections and shows high level of antibiotic resistance. integrons are one of the transposable elements in bacteria and their role in antibiotic resistance has been well demonstrated. the aim of this study was a molecular characterization of the integron genes and the determination of the resistance or sensiti...

Antibiotic-resistant bacteria have posed a grave threat to public health by causing a number of nosocomial infections in hospitals. Mathematical models have been used to study transmission dynamics of antibiotic-resistant bacteria within a hospital and the measures to control antibiotic resistance in nosocomial pathogens. Studies presented in Lipstich et al. (Proc Natl Acad Sci 97(4):1938-1943,...

The rapid and ongoing spread of antibiotic resistance poses a serious threat to global public health. The indiscriminant use of antibiotics in agriculture and human medicine along with increasingly connected societies has fueled the distribution of antibiotic-resistant bacteria. These factors together have led to rising numbers of infections caused by multidrug-resistant and pan-resistant bacte...

2 3 The prevalence of antibiotic-resistant bacteria in the marine environment is a growing 4 concern, but the degree to which marine mammals, seabirds and fish harbor these organisms is 5 not well documented. This project sought to identify the occurrence and patterns of antibiotic 6 resistance in bacteria isolated from vertebrates of coastal waters in the northeastern United 7 States. 472 isol...

BACKGROUND/AIMS Recent evidence has suggested that appendix plays a pivotal role in the development and preservation of intestinal immune system. The aim of this study is to examine whether prior appendectomy is associated with an increased risk for the development of antibiotic-resistant bacteria in bacteremia from biliary tract infection (BTI). METHODS Charts from 174 consecutive cases of b...