نتایج جستجو برای: anti proliferative
تعداد نتایج: 388579 فیلتر نتایج به سال:
Angiogenesis, in particular anti-angiogenesis, is an area of particular therapeutic interest in cancer treatment. Several anti-angiogenic agents are in the final stages of clinical trials. One of these agents, thalidomide, best known for its teratogenic potential, is showing promise against several tumor types. Thalidomide has been shown previously to require bio-activation to exert its anti-an...
The aim of this study was to compare ongoing production of anti-C1q antibodies (anti-C1q) in peripheral blood with serum anti-C1q levels in patients with systemic lupus erythematosus (SLE), especially in patients with nephritis. Using the ELISPOT technique for the detection of IgG and IgA anti-C1q production, 21 patients with active SLE were investigated. ELISAs for IgG and IgA anti-C1q were co...
Abstract Background: Oak placenta(jaft) extract has potent antioxidant, anti-proliferative and anti-cancer activity, and other therapeutic properties. The aim of this study is to investigate the effect of the hydroalcoholic extract of the Jaft on the cytotoxicity of cisplatin on the AGS gastric adenocarcinoma cell line. Materials and methods: The MTT method was used to check cell viability...
Transforming growth factor-beta (TGFbeta) has a crucial role in tissue homeostasis and disruption of the TGFbeta pathway has been implicated in many human diseases including cancer. As a potent inhibitor of epithelial cell proliferation, TGFbeta is a tumor suppressor. Tumor cells evade the antitumoral effect of TGFbeta, either by acquiring somatic mutations that blunt TGFbeta signaling or by se...
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