The effect of the anti-hypertensive drug eprosartan on metabolic parameters is currently not extensively documented. We evaluated the effect of eprosartan on parameters involved in atherogenesis, oxidative stress and clotting activity. This open-label unblinded intervention study included 40 adult patients with essential hypertension taking eprosartan. Eprosartan significantly reduced by 8% (p<...

High blood pressure is considered one of the major risk factors for heart disease. In addition to evidence low disease and death with adequate control pressure, antihypertensive treatment still less effective in clinical practice. It well documented that there a decrease cardiovascular events, such as stroke MI, potent therapies combat high pressure. This, however, generally believed be result ...

IMPORTANCE Randomized trials of anti-hypertensive treatment demonstrating reduced risk of cardiovascular events in older adults included participants with less comorbidity than clinical populations. Whether these results generalize to all older adults, most of whom have multiple chronic conditions, is uncertain. OBJECTIVE To determine the association between anti-hypertensive medications and ...

Hypertension is associated with low-grade inflammation, and Toll-like receptor 4 (TLR4) has been shown to be linked to the development and maintenance of hypertension. This study aimed to investigate the effects of scutellarin (administered by oral gavage daily for 2 weeks) on brain TLR4/nuclear factor kappa B-(NF- κ B-) mediated inflammation and blood pressure in renovascular hypertensive (usi...

1. In Dahl S rats becoming hypertensive while on a diet of high NaCl content there appears to be a blood-borne humoral agent which produces vasoconstriction in a bioassay using the isolated hindquarters of rats. 2. This vasoconstrictor effect strongly suggests the presence of a humoral pressor agent or the lack of a vasodilator agent in the blood of hypertensive S rats. 3. The vasoconstrictor e...

Selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) as well as acetaminophen belong to the most widely prescribed therapeutic agents worldwide. Their efficacy in pain relief notwithstanding, the use of NSAIDs is associated with an increased cardiovascular risk, which can be partly attributed to their blood pressure raising potential. Adequately powered placebo-controlled ...

Long-term adherence or compliance with anti-hypertensive drug therapy is poor. It has been estimated that within the first year of treatment 16-50% of hypertensives discontinue their anti-hypertensive medications. Even among those who remain on therapy long term, missed medication doses are common. Epidemiological studies have shown that drug-treated hypertensives have higher blood pressures th...

Background and Aim: High blood pressure is a common cardiovascular disease. Most cardiovascular medications have adverse oral side effects. This study aimed to determine the prevalence of oral manifestations associated with the intake of anti-hypertensive medications. Materials and Methods: This cross-sectional analytical study examined 142 patients with a history of hypertension referred to D...

Nowadays beverages are consumed which has high bioactive compound. Both cocoa and Hibiscus-flower extract have antioxidant effect their combined increases the free radical scavenging potentials of beverages. Hibiscus Sabdariffa various such as Anti-hypertensive effect, Anti-oxidant Diuretic Anti-spasmodic etc. The dried flower is used to prepare Tea, Syrup, Jams-jellies phytochemicals studies f...