BACKGROUND Improved targeted therapies for rheumatic diseases were developed recently resulting in a better prognosis for affected patients. Nowadays, patients are living longer and with improved quality of life, including fertility potential. These patients are affected by impaired reproductive function and the causes are often multifactorial related to particularities of each disease. This re...

Our goal was to determine the endocrine and post-coital anti-fertility activity of CDB-2914. Concurrent administration of progesterone to rats on day 4 post-mating blocked the anti-fertility activity of a single oral 2 mg dose of CDB-2914. CDB-2914 did not exhibit progestational activity in the oestradiol-primed immature female rabbit at doses that exhibited anti-progestational activity. CDB-29...

the naturally occurring antioxidants: vitamin e, β-carotene and vitamin c are known to ameliorate theoxidative stress generated during various physiological and pathological conditions. the oxidative stress mayoccur at different sites, different times, and by different mechanisms in the animal system. lower levels ofthe anti-oxidant vitamins are associated with poor fertility and production lev...

Increasing community awareness of the moral and animal welfare issues associated with conventional pest animal control has focused interest on non-lethal alternatives, such as fertility control. In Australia, animal welfare organizations have proposed fertility control as a solution to pest problems with feral horses and kangaroos. Wildlife damage control achieved by non-lethal, non-toxic and h...

Triptolide is an important active component of Tripterygium wilfordii Hook F (TWHF) and possesses anti-inflammatory, immunosuppressive, male anti-fertility, and anticancer properties. A new method combining different techniques, including solid-liquid extraction, liquid-liquid partition, column chromatography and high-speed counter-current chromatography (HSCCC) but avoiding the use of chlorofo...

Papaya (Carica papaya L.) is well known for the its exceptional nutritional and medicinal properties throughout world. From past, whole plant including leaves, seeds, ripe unripe fruits their juice used as a traditional medicine. The fruit has large oval shape, yellowish – green yellow flesh. Phytochemically it contains enzymes papain, chymopapin, which biologically actives value. They also con...

Fertility is possibly the most important capability contained within living cells or species. Therefore, finding the most efficacious way to enhance or promote fertility is the main goal of all living things. To best manage nature's strong predisposition for fertility, plant-based traditional medicines for birth control have long been incorporated into medical practices throughout the world, in...

The pathophysiology of iron-induced compromised fertility in women with thalassemia major (TM) was evaluated in 26 adult TM females. Low gonadotropin secretion resulted in reduced ovarian antral follicle count and ovarian volume, but levels of anti-müllerian hormone (AMH), a sensitive marker for ovarian reserve independent of gonadotropin effect, were mostly normal. AMH correlated with non-tran...