objectives: this study sought to assess the effect of curcumin nanoparticles (curcnps) on antimicrobial property and shear bond strength (sbs) of orthodontic composite to bovine enamel. materials and methods: in this in vitro, experimental study, 1%, 5% and 10% curcnps were added to transbond xt composite. stainless steel brackets were bonded to 48 sound bovine incisors in four groups (n=12) us...

Background and Objective: The endophytes are the fungi or bacteria that live within a plant in a symbiotic relationship. This study aimed to investigate the effect of isolated bacterial endophytes from Allium jesdianum on some bacterial pathogens such as Staphylococcus aureus, Escherichia coli as well as pathogenic fungi, including Trichophyton mentagrophytes and Candida albicans. Materials an...

objective: punica granatum has been used for many years in folk medicine due to several purposes. the aim of the present study was to evaluate the effect of methanolic extract of punica granatum peel (mepgp) against streptococcus mutans, staphylococcus aureus, streptococcus salivarius, streptococcus sanguinis, staphylococcus epidermidis, actynomyces viscosus, lactobacillus acidophilus and candi...

  Background and Objectives: Blood stream infections cause significant morbidity and mortality in the world. In this study, we aimed at describing the organisms responsible for septicemia in 2006-2007 and their antimicrobial susceptibility that might lead to proper selection of antimicrobial agents in hospitalized patients with suspected sepsis. Materials and Methods: Microbiology reports of ...

A series of potent antibacterial agents have been prepared. These agents are penems carrying a lactone ring in the C-2 position. Excellent activity against Gram-positive and Gram-negative organisms--except Pseudomonas aeruginosa--was found.

Fused polyheterocyclic derivatives are available by annulation of a tetramate scaffold, and been shown to have antibacterial activity against a Gram-negative, but not a Gram-positive, bacterial strain. While the activity is not potent, these systems are structurally novel showing, in particular, a high level of polarity, and offer potential for the optimization of antibacterial activity.

An efficient synthesis of two new N-acetyl-4'-arylphenylalanines is described together with their incorporation into a number of cationic peptoid antibacterial agents, one of which had an MIC of 7.8 microg/mL against Staphylococcus aureus.

To our knowledge, previous population-based surveys have not assessed misconceptions about antibacterial drug use over time. We documented a 26.3% decline in a key misconception in California women in 2003 compared to 2000; declines varied significantly by education level. Educational campaigns specifically designed to influence important subpopulations are needed.

Fluoroquinolones are one of the most promising and vigorously pursued areas of contemporary antiinfective chemotherapy depicting broad spectrum and potent activity. They have a relatively simple molecular nucleus, which is amenable to many structural modifications. These agents have several favorable properties such as excellent bioavailability, good tissue penetrability and a relatively low in...

In studies of the interactions of antibacterial agents, it became important to try to elicit bacterial resistance to antibiotics in the experimental animal. Since this proved to be unexpectedly difficult, attention was directed to the process by which bacteria acquire resistance during exposure in vivo. The present paper is concerned with the incidence of streptomycin resistance in strains of s...