Two new dimeric anthraquinone derivatives, bulgareone A(1) and bulgareone B(2), were isolated from the fruit bodies of Bulgaria inquinans. Their structures were elucidated on the basis of extensive spectroscopic analysis. The in vitro cytotoxic activity of compounds 1 and 2 was assayed. They displayed inhibitive activities against human cancer cell lines HL60 and K562.

Anthraquinone (AQ) derivatives play a prominent role in medicine and also in textile industry. Bromaminic acid (1-amino-4-bromoanthraquinone-2-sulfonic acid) is an important precursor for obtaining dyes as well as biologically active compounds through the replacement of the C4-bromo substituent with different (ar)alkylamino residues. Here we report methods for the synthesis of bromaminic acid a...

Rhubarb (Rheum emodi) is an important medicinal plant, which finds an extensive use in Ayurveda and Unani system of medicine. Rhubarb (Rheum emodi, family Polygonaceae) has been traditionally used as diuretic, liver stimulant, purgative/cathartic, stomachic, Antitumour, anticholesterolaemic, antiseptic, wound healer, antidiabetic and tonic. The most important constituents from rhubarb are the f...

Chinese herbal medicine preparations are widely available and often regarded by the public as natural and safe remedies for a variety of medical conditions. Nephropathy caused by Chinese herbs has previously been reported, usually involving the use of aristolochic acids. We report a 23-year-old woman who developed acute renal failure following prolonged use of a proprietary Chinese herbal slimm...

The growth-inhibiting activity of Tabebuia impetiginosa Martius ex DC dried inner bark-derived constituents against Helicobacter pylori ATCC 43504 was examined using paper disc diffusion and minimum inhibitory concentration (MIC) bioassays. The activity of the isolated compounds was compared to that of the commercially available anti-Helicobacter pylori agents, amoxicillin, metronidazole, and t...

the synthesis of 1,5-dihydroxy-9,10-anthraquinone (17); (1,5-dha) was accomplished during, attempts towards the synthesis one of its derivatives called anthralin (1,8-dihydroxy-9-anthrone) which is known as an antipsoriasis drug since 1916 [1]. this work is a new reigiospecilic preparation of 1,5-dha based on friedel-crafts reaction starting from 1,4-dimethoxybenzene. this synthetic route, in a...