The objective: to substantiate and evaluate the improvement of pre-gravida preparation in women with a history combined infertility factors. Materials methods. We examined 102 who were diagnosed two factors simultaneously – tubal origin associated anovulation caused by hyperprolactinemia polycystic ovary syndrome. All patients divided into groups according three-month regimen: 1st group (52 wom...

The histogenesis, pathogenesis, and endocrine background of endometrial cancer are reviewed. The histogenesis can be traced in graded steps through phases which have been designated as: 1) cystic hyperplasia, 2) adenomatous hyperplasia, 3) ana plasia, and 4) carcinoma in situ. A similar sequence of events has been observed in experimental animals when endometrial cancer was induced by the use o...

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy associated with infertility and metabolic disorder in women of reproductive age. Although the clinical and biochemical features are heterogeneous with individuals, the most widely accepted clinical characteristics of PCOS are oligo- or anovulation combined with hyperandrogenism. With the higher rate of implantation failure after...

Patients suffering from normogonadotrophic anovulation and infertility are initially treated with clomiphene citrate. Those who do not respond to clomiphene citrate usually receive gonadotrophin treatment which is labour-intensive, expensive, and associated with an increased risk of multiple pregnancies and ovarian hyperstimulation syndrome. We treated 22 patients with clomiphene resistant norm...

n Evidence summary Polycystic ovarian syndrome is a condition of unexplained hyperandrogenic chronic anovulation that affects at least 4% of women of reproductive age. Because PCOS is a clinical syndrome, no single diagnostic criterion is sufficient for diagnosis. Clinical features include menstrual irregularities or infertility, hirsutism, male-pattern balding, acne, ovarian enlargement, and s...

World Health Organisation (WHO) type II anovulation is defined as normogonadotrophic normoestrogenic anovulation and occurs in approximately 85% of anovulatory patients. Polycystic ovary syndrome (PCOS) is the most common form of WHO type II anovulatory infertility and is associated with hyperandrogenemia (1,2). Moreover, PCOS is the most common endocrine abnormality in reproductive age women. ...