Linear porokeratosis is one of the infrequent variants of porokeratosis, a rare disorder of keratinization that may develop into several epidermal malignancies, among them squamous cell carcinoma. Clinical surveillance for malignancy is imperative, but in cases when large or many lesions are present, surgical removal of porokeratosis lesions would result in an unfavorable amount of scarring. A ...

Porokeratosis is a disorder of keratinisation whose pathogenesis is yet unclear. It has been postulated that it results from the proliferation of an abnormal clone of keratinocytes, triggered by several factors, such as immunosuppression or prolonged ultraviolet exposure. Various clinical forms are recognized whose common denominator is a keratotic ring surrounding a central zone of atrophy. Th...

1. Wade TR, Ackerman AB. Cornoid lamellation. A histologic reaction pattern. Am J Dermatopathol 1980; 2: 5 ± 15. 2. Schamroth JM, Zlotogorski A, Gilead L. Porokeratosis of MibelliÐoverview and review of the literature. Acta Derm Venerol 1997; 77: 207 ± 213. 3. Fields LL, White CR Jr, Maziarz RT. Rapid development of disseminated super®cial porokeratosis after transplant induction therapy. Bone ...

It is reported on a 72-year-old pensionary who developed one year ago a disseminated superficial actinic porokeratosis on the lower legs after chronic sun exposure during twenty summers. The diagnostic features and therapeutic schedules are summarized and the role as praecancerosis is emphasized.

508 Ann Dermatol Received January 12, 2016, Revised July 8, 2016, Accepted for publication August 13, 2016 Corresponding author: Yoshihiro Tokudome, Laboratory of Dermatological Physiology, Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan. Tel: 81-49-271-8140, Fax: 81-49-271-8140, E-mail: tokudome@ josai.ac.jp This is an Open Access article di...

© 2010 The Authors. doi: 10.2340/00015555-0800 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Porokeratosis (PK) is a heterogeneous group of hereditary or acquired disorders of keratinization with a broad clinical spectrum and various aetiologies. Common to all PK is the typical histological feature of a cornoid lamella, which corresponds to the hyperkeratotic rim of...

Disseminated superficial actinic porokeratosis is a rare photodistributed disorder that has occasionally been reported in association with psoriasis. Treatment of psoriasis with phototherapy may trigger the onset of porokeratosis in some cases. In other cases, the coexistence of these disorders may be coincidental. Clinical inspection of lesions of coexisting porokeratosis and psoriasis reveals...

A 15-year-old girl underwent allogenic bone marrow transplantation for neuroblastoma. few years later, she noticed a round lesion on her left buttock. Since the had been asymptomatic and never grown, more than 20 passed before saw local doctor to consult about it. Although was suspected be tinea corporis, no fungi were found microscopic examination. Subsequently, administered topical corticoste...

Sir, Disseminated porokeratosis palmaris and plantaris (DPPP), a subtype of porokeratosis Mibelli, is a rare autosomal dominant genodermatosis first described by Guss et al. in 1971 (1). An early review of the literature showed that 7% of 250 patients with porokeratosis subsequently developed skin tumours (2). Squamous cell carcinomas (SCC), Bowen’s disease (BD), and rarely, basal cell carcinom...

Porokeratosis is an abnormal disease of keratinization of epidermis. It is clinically characterized by margins covered with keratin layer and it typically has an atrophied macule with a protruded, circular form. Histopathologically, it shows the findings of cornoid lamella. Risk factors for its development include organ transplantation, long-term use of corticosteroids, immunocompromised status...