Oxidative stresses induced by reactive oxygen species (ROS) have been shown to be involved in several physiological and pathophysiological processes, such as cell proliferation and differentiation. Steroid hormones can protect cells against apoptosis or induce cell proliferation by several mechanisms. Among androgenic hormones, dihydrotestosterone (DHT) is generated by a 5alpha- reduction of te...

Little is known regarding the role of androgenic hormones in the maintenance of myosin heavy chain (MHC) composition of rodent masticatory muscles. Because the masseter is the principal jaw closer in rodents, we felt it was important to characterize the influence of androgenic hormones on the MHC composition of the masseter. To determine the extent of sexual dimorphism in the phenotype of masse...

Prairie voles (Microtus ochrogaster) are a socially monogamous species and both sexes are parental after the birth of pups. In contrast, sexually inexperienced adult prairie voles differ in their behavior towards pups such that virgin males are paternal whereas virgin females are often infanticidal. To test whether there exists a discrete perinatal 'sensitive period' during which gonadal hormon...

T hat androgenic hormones stimulate erythropoiesis in animals and man has been known for many years.1’2 The principle mechanism for this activity probably results from an increased production of erythropoietin since both serum and urine levels are elevated by androgens.35 Even when plasma erythropoietin content is high, as in most anemias, further enhancement may occur after administration of t...

T hat androgenic hormones stimulate erythropoiesis in animals and man has been known for many years.1’2 The principle mechanism for this activity probably results from an increased production of erythropoietin since both serum and urine levels are elevated by androgens.35 Even when plasma erythropoietin content is high, as in most anemias, further enhancement may occur after administration of t...

A survey is given of experimental studies on the influence of treatment with androgenic hormones in vivo on various intermediary reactions involved in ribonucleic acid (RNA) and protein synthesis in the prostate gland and seminal vesicle, with particular reference to the control of the growth and functional differentiation of these organs by testosterone and related steroids. Studies on the inf...

T hat androgenic hormones stimulate erythropoiesis in animals and man has been known for many years.1’2 The principle mechanism for this activity probably results from an increased production of erythropoietin since both serum and urine levels are elevated by androgens.35 Even when plasma erythropoietin content is high, as in most anemias, further enhancement may occur after administration of t...

To assess the effect of urinary bisphenol A (BPA) on repeated measurements of androgenic hormones and metabolic indices, we used multivariate analysis of variance (MANOVA) adjusted for potential confounders at baseline. During July to August 2011, 80 preadolescent girls enrolled in the Ewha Birth & Growth Cohort study participated in a follow-up study and then forty-eight of them (60.0%) ca...

T hat androgenic hormones stimulate erythropoiesis in animals and man has been known for many years.1’2 The principle mechanism for this activity probably results from an increased production of erythropoietin since both serum and urine levels are elevated by androgens.35 Even when plasma erythropoietin content is high, as in most anemias, further enhancement may occur after administration of t...