Ixodes scapularis transmits the agent of human granulocytic anaplasmosis, among other pathogens. The mechanisms used by the tick to control Anaplasma phagocytophilum are not known. We demonstrate that the I. scapularis Janus kinase (JAK)-signaling transducer activator of transcription (STAT) pathway plays a critical role in A. phagocytophilum infection of ticks. The A. phagocytophilum burden in...

Las ehrlichiosis y anaplasmosis canina son enfermedades transmitidas por garrapatas, provocadas bacterias del genero Ehrlichia Anaplasma. Debido a sus multiples manifestaciones clinicas, su diagnostico es un reto para el veterinario. La distribucion de estos hemoparasitos incluye areas donde principal vector, Rhipicephalus sanguineus esta presente. Este estudio fue disenado determinar la presen...

2. Strasek Smrdel K, Tozon N, Duh D, Petrovec M, Avsic Zupanc T. Diversity of groESL sequences of Anaplasma phagocytophilum among dogs in Slovenia. Clin Microbiol Infect. 2009;15(Suppl 2):79– 80. http://dx.doi.org/10.1111/j.1469-0691. 2008.02201.x 3. Masuzawa T, Uchishima Y, Fukui T, Okamoto Y, Muto M, Koizumi N, et al. Detection of Anaplasma phagocytophilum from wild boars and deer in Japan. J...

Anaplasma phagocytophilum is a bacterial parasite of human and animal granulocytes. Instances of granulocytic anaplasmosis (formerely HGE--human granulocytic ehrlichiosis) have been noted in Europe, including northeastern Poland. Here the results of studies on the occurrence of Anaplasma pathogens in ticks Ixodes ricinus in Western Pomerania are presented. 4,6% of the tick population was infect...

We examined the reservoir potential of white-tailed deer for Anaplasma phagocytophilum. Results suggest that white-tailed deer harbor a variant strain not associated with human infection, but contrary to published reports, white-tailed deer are not a reservoir for strains that cause human disease. These results will affect surveillance studies of vector and reservoir populations.

Blood samples collected from wild deer in Missouri in November of 2000 and 2001 were positive by PCR assays for Ehrlichia chaffeensis (50 of 217; 23%), Ehrlichia ewingii (44 of 217; 20%), and Anaplasma species (214 of 217; 99%). Nucleotide sequences of selected amplicons from the assay for anaplasma matched sequences of the white-tailed deer agent. Serologic analysis of 112 deer sampled in 2000...

Dermacentor albipictus (Packard) is a North American tick that feeds on cervids and livestock. It is a suspected vector of anaplasmosis in cattle, but its microbial flora and vector potential remain underevaluated. We screened D. albipictus ticks collected from Minnesota white-tailed deer (Odocoileus virginianus) for bacteria of the genera Anaplasma, Ehrlichia, Francisella, and Rickettsia using...

The present study aimed to determine the complete citrate synthase (gltA) and heat-shock protein (groEL) gene sequences of Anaplasma bovis and to infer phylogenetic relationships within the genus Anaplasma. Multiple alignments from single and concatenated sequences of the 16S rRNA, gltA and groEL genes of the genus Anaplasma were subjected to phylogenetic analyses. Percent identities of A. bovi...

Anaplasma phagocytophilum has long been known to cause tick-borne fever in ruminants and has been identified more recently as the causative agent of the emerging disease human granulocytic anaplasmosis. The related organism Anaplasma marginale uses gene conversion of the expression site for two major outer membrane proteins (OMPs) to generate extensive sequence and antigenic variation in these ...