Chantaleela recipe is indicated for relieving fever in Thai traditional folk medicine. In the present study, Chantaleela recipe was investigated for anti-inflammatory, analgesic, antipyretic and anti-ulcerogenic activities. In preliminary investigation Chantaleela recipe was found to exert an inhibitory activity on the acute phase of inflammation as seen in ethyl phenylpropiolate-induced ear ed...

A novel series of 2-(substituted phenoxy)-N-(1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)acetamide and N-(2-bromocyclohexyl)-2-(substituted phenoxy)acetamide derivatives having cyclohexyl nucleus as common in both types were synthesized and assessed for their antiinflammatory activity by a carrageenan induced rat paw oedema method, analgesic activity by Eddy’s hot plate method and antipyretic acti...

An aqueous extracts of stem and leaves of Boerhaavia Diffusa (Aq.EBD) and leaves of Anisochilus Carnosus (Aq.EAC) was studied for hepatoprotective, analgesic and antipyretic activity. Hepatotoxicity was introduced in Albino rats of either sex by intraperitoneal injection of CCl4 (in olive oil). Tail immersion method and Hot plate method in mice were studied for analgesic activity, Yeast induced...

An aqueous extracts of stem and leaves of Boerhaavia Diffusa (Aq.EBD) and leaves of Anisochilus Carnosus (Aq.EAC) was studied for hepatoprotective, analgesic and antipyretic activity. Hepatotoxicity was introduced in Albino rats of either sex by intraperitoneal injection of CCl4 (in olive oil). Tail immersion method and Hot plate method in mice were studied for analgesic activity, Yeast induced...

Purpose: The aqueous fruit pulp extract of Hunteria umbellata K. Schum is used traditionally for the treatment of various fevers. The purpose of this study was to evaluate the extract for antipyretic and analgesic activity, and determine its probable mechanism of action. Methods: Pyrexia was induced in rabbits by intravenous injection of 10 5 CFU of E. coli/kg. Rectal temperature was monitored ...

The pharmacological activities of the n -butanol alkaloids extracted from the stem bark of Hunteria zeylanica (Retz) Gardn. ex Thw. ( H. zeylanica ) and its major constituent, strictosidinic acid, on nociceptive response using writhing and hot plate tests, the antipyretic activity in yeast-induced fever, pentobarbital-induced sleep, and locomotor activity were examined in mice. Oral administrat...

The present study was designed to investigate the gastroprotective, analgesic, and antipyretic effects of curcumin (Cur), the major constituent of turmeric. Acetylsalicylic acid (ASA) was used in this study as a standard drug for comparison. The analgesic activity was measured using the Hot-Plate Test. The antipyretic and antiulcer effects were assessed using yeast-induced pyrexia and gastric u...

Chronic inflammation is an underlying etiological factor in carcinogenesis; nonsteroidal anti-inflammatory drugs (NSAIDs) and their chemically modified NO-releasing prodrugs (NO-NSAIDs) are promising chemopreventive agents. The aim of this study was to conduct a head-to-head comparison between two NO-ASAs possessing different NO donor groups, an organic nitrate [3-nitrooxyphenyl acetylsalicylat...

This study was intended to evaluate the analgesic anti-inflammatory and antipyretic activity of ethanolic extract of Cissus quadrangularis in experimental standard modals i.e. albino rats following oral administration. The results showed that the ethanolic extract significantly reduce the edema induced by carrageenan within 1 to 5 hrs. post dosing at all the dose levels used. On the analgesic p...