There are unexplained links between human exposure to aluminium and the incidence, progression and aetiology of Alzheimer's disease. The null hypothesis which underlies any link is that there would be no Alzheimer's disease in the effective absence of a body burden of aluminium. To test this the latter would have to be reduced to and retained at a level that was commensurate with an Alzheimer's...

A 28-year-old woman presented with an axillary eczema that occurred after using deodorants. Patch testing revealed contact allergy to aluminium chloride. With avoidance of aluminium-containing deodorants, the eczema cleared completely. Aluminium and its salts are widely used but contact allergy to them is uncommon. It is occasionally recognised incidentally as a reaction to aluminium Finn Chamb...

Aluminium is one of the trace elements with a moderate toxic effect on living organisms. This study is to assess the influence of aluminium chloride and aluminium hydroxide intake on biochemical parameters in experimental animals for 21 days. Administration of aluminium chloride and aluminium hydroxide at a dose of 300mg/kg of body weight significantly elevates blood serum urea and creatinine c...

This paper describes a method for the sensitive detection of aluminium in biological tissues by real time confocal laser scanning microscopy after staining with lumogallion. The method enabled detection of aluminium > or = 9 micrograms g-1 in bone and is more sensitive than the conventional histochemical methods with aluminium and solochrome azurine, etc. Lumogallion reacts specifically with al...

Iliac bone aluminium was determined by neutron activation analysis in 34 patients with chronic renal failure and in eight control subjects. In 17 patients treated by haemodialysis there was a significant increase in the amount of aluminium (mean +/- SE = 152 +/- 30 ppm bone ash). In eight patients treated by haemodialysis and subsequent renal transplantation, bone aluminium was still significan...

Aluminium Phosphide poisoning and glucose‐6‐phosphate dehydrogenase deficiency are two commonly seen clinical presentations in Iran. However, hemolysis associated with Aluminium Phosphide poisoning is very rare. We report a case of concurrent Aluminium Phosphide poisoning and glucose‐6‐phosphate dehydrogenase deficiency in a 24 year old man presenting with intravascular hemolysis. Key words...

The causes of declines in bees and other pollinators remains an on-going debate. While recent attention has focussed upon pesticides, other environmental pollutants have largely been ignored. Aluminium is the most significant environmental contaminant of recent times and we speculated that it could be a factor in pollinator decline. Herein we have measured the content of aluminium in bumblebee ...

BACKGROUND Aluminium-containing phosphate binders have long been used for treatment of hyperphosphatemia in dialysis patients. Their safety became controversial in the early 1980's after reports of aluminium related neurological and bone disease began to appear. Available historical evidence however, suggests that neurological toxicity may have primarily been caused by excessive exposure to alu...

The present experiment was carried out to investigate the effectivness of -lipoic acid in allevating the toxicity of aluminium phosphide on biochemical parameters, free radicals and enzyme activities in plasma, liver and kidney of male rats. Animals were orally treated with aluminium phosphide, -lipoic acid and their combination for 30 consecutive days. Treatment with aluminium phosphide led to...

Work-related asthma has been documented in workers employed in the primary aluminium industry and in the production of aluminium salts. The role of aluminium in the development of occupational asthma has, however, never been convincingly substantiated. We investigated a subject who experienced asthmatic reactions related to manual metal arc welding on aluminium. Challenge exposure to aluminium ...