Melaleuca (Melaleuca alternifolia) essential oil (MEO), commonly known as tea tree oil, is popularly used in skincare products. In the current study, we investigated the biological activity of a commercially available MEO (with terpinen-4-ol as the major active component) in pre-inflamed human dermal fibroblasts, which were designed to simulate chronic inflammation. We analyzed the levels of se...

AIMS To investigate the in vitro antifungal activity of the components of Melaleuca alternifolia (tea tree) oil. METHODS AND RESULTS Activity was investigated by broth microdilution and macrodilution, and time kill methods. Components showing the most activity, with minimum inhibitory concentrations and minimum fungicidal concentrations of < or =0.25%, were terpinen-4-ol, alpha-terpineol, lin...

In organic phytosanitary management of vineyards, it is crucial to understand the available pathogen control alternatives in order progress towards a more sustainable form viticulture. The objective this study was evaluate efficacy seven biofungicides registered Chile for prevention and treatment Botrytis Bunch Rot (BBR), test novel fungicide composed chitosan riboflavin (CH-RF). Biofungicides ...

Süs bitkilerinin içerisinde önemli bir yere sahip olan gülün en zararlılarından birisi de Gül yaprak biti Macrosiphum rosae (L.) (Hemiptera: Aphididae)’dir. M. rosae, bitki öz suyunu emerek beslenir. bitleri, koloniler halinde sürgün, ve tomurcuklarda bulunur. tomurcuk yeni sürgünlerin büyümesini geciktirmektedir. Bu nedenle bu zararlılara karşı genellikle kimyasal mücadele uygulanmaktadır. Anc...

The aim of this study was to evaluate the activity of fluconazole against 32 clinical strains of fluconazole-resistant Candida albicans, and C. albicans ATCC 10231 reference strain, after their exposure to sublethal concentrations of tea tree oil (TTO) or its main bioactive component terpinen-4-ol. For all tested fluconazole-resistant C. albicans strains TTO and terpinen-4-ol minimal inhibitory...

BACKGROUND There are several synergistic methods available. However, there is a vast discrepancy in the interpretation of the synergistic results. Also, these synergistic methods do not assess the influence the tested components (drugs, plant and natural extracts), have upon one another, when more than two components are combined. METHODS A modified checkerboard method was used to evaluate th...

background: melaleuca alternifolia (tea tree) essential oil has been traditionally used in the ayurvedic system of medicine for healing burns, infections and seborrheic dermatitis. but yet, no controlled human study has determined its efficacy. objective: the goal of the current study was to compare the efficacy of 5% tea tree essential oil (tto) gel with placebo in the treatment of mild to mod...