Hemoglobin (Hb) Constant Spring is an alpha-thalassemic hemoglobinopathy that is a major cause of severe alpha-thalassemia in Southeast Asians. The difficulty of diagnosing Hb Constant Spring using standard electrophoretic methods has led to interest in DNA-dependent diagnostic methods. The methods developed have had to contend with the high degree of homology of the alpha 2-globin gene (the si...

Recently, we have benchmarked and tuned the MILC code on a number of architectures including Intel Itanium and Pentium IV (PIV), dual-CPU Athlon, and the latest Compaq Alpha nodes. Results will be presented for many of these, and we shall discuss some simple code changes that can result in a very dramatic speedup of the KS conjugate gradient on processors with more advanced memory systems such ...

We introduce a sensor molecule, AS140-MFC, consisting of a covalent adduct of an Ala-to-Cys mutant of alpha-synuclein with the 3-hydroxychromone dual emission dye MFC. We show that the AS140-MFC construct is a multiparametric fluorescent probe suitable for the continuous monitoring of protein aggregation and is sensitive to the early and intermediate stages of alpha-synuclein aggregation, a pro...

In this paper we will consider noncommutativity that arises from bosonic T-dualization of type II superstring in presence Ramond-Ramond (RR) field, which linearly depends on the coordinates x ? $x^\mu$ . The derivative RR field C ? ? $C^{\alpha \beta }_\mu$ is infinitesimal. We employ generalized Buscher procedure can be applied to cases have coordinate dependent background fields. Bosonic part...

‎in this paper‎, ‎first we develop the duality concept for $g$-bessel sequences‎ ‎and bessel fusion sequences in hilbert spaces‎. ‎we obtain some results about dual‎, ‎pseudo-dual ‎and approximate dual of frames and fusion frames‎. ‎we also expand every $g$-bessel ‎sequence to a frame by summing some elements‎. ‎we define the restricted isometry property for ‎$g$-frames and generalize some resu...

The entanglement wedge cross section (EWCS) is numerically investigated statically and dynamically in a five-dimension AdS-Vaidya spacetime with Gauss-Bonnet (GB) corrections, focusing on two identical rectangular strips the boundary. In static case, EWCS increases as GB coupling constant $\alpha$ disentangles at small separation between for smaller $\alpha$. For dynamic such monotonic relation...

An experimental investigation was performed with two aims: (1) to clarify the existence of the dual leading-edge vortices (i.e. two vortices with the same sense of rotation located close to the leading edge above the leeward wing surface) observed on flapping wings in previous studies; (2) to study systematically the influences of kinematic and geometric parameters on such a vortical structure....

Owing to their unique functions in regulating glucose, lipid and cholesterol metabolism, PPARs (peroxisome proliferator-activated receptors) have drawn special attention for developing drugs to treat type-2 diabetes. By combining the lipid benefit of PPAR-alpha agonists (such as fibrates) with the glycemic advantages of the PPAR-gamma agonists (such as thiazolidinediones), the dual PPAR agonist...