We present an e cient method for the comparison of protein structures, allowing swiveling motions. In all currently available methodologies developed and applied to the comparisons of protein structures, the molecules are considered to be rigid objects. The method described here extends and generalizes current approaches to searches for structural similarity between molecules by viewing protein...

In “Tragedy and Resentment” Ulrika Carlsson claims that there are cases when we justified in feeling non-moral resentment against someone who harms us without wronging us, the harm either consists their attitude towards or emotional suffering triggered by attitudes. Since they had no duty to protect from harm, objectionable is not disrespect but a failure show love, admiration, appreciation for...

One dilemma faced by policy makers is the choice between banning a harmful behavior and allowing to continue but with mitigated harm. This latter approach––a harm reduction strategy––is often efficacious, yet policies of this sort can be unpopular if people morally oppose target (MacCoun, 2013). raises interesting questions for understanding how judgments harmfulness relate moral opposition. In...