Allium cepa is a popular recipe used traditionally to treat diabetes, cardiovascular diseases, cancer, wounds and infections. The acute sub-acute oral toxicity profile of the aqueous extract peels were evaluated in wistar albino rats order determine its safety for use traditional medicine. median lethal dose (LD 50) body weights food intake determined. peel was carried out accordance with OECD ...

The genotoxic effects of the industrial effluent from a paint (100%, 50%, 25%, 10%, 5%, 1%, 0.50% and 0.25%) manufacturing company in Ikotun, Lagos was evaluated using the root meristem cells of Allium cepa. chromosomal aberration assays were used to determine the mitotic index and chromosome aberration rate. There was a significant difference (p<0.05) in the average root length of Allium cepa ...

The effects of onion peel extract (OPE) in collagen (5 μg/mL)-stimulated washed rat platelet aggregation were investigated. OPE inhibited platelet aggregation via inhibition of aggregation-inducing molecules, intracellular Ca(2+) and thromboxane A2 (TXA2) by blocking cyclooxygenase-1 (COX-1) and TXA2 synthase (TXAS) activities in a dose-dependent manner. In addition, OPE elevated the formation ...

The aim of this study was to evaluate the biological and chemical response of Allium cepa L. exposed to inorganic selenium compounds. Besides the investigation of the total content of selenium as well as its chemical speciation, the Allium test was used to evaluate the growth of onion roots and mitotic activity in the roots' meristem. The total content of selenium was determined by inductively ...

Higher plants, an important material for genetic tests to monitor various pollutant present in the environment. Among the plant species, Alium cepa has been used to evaluate chromosome aberrations and disturbances in the mitotic cycle. Now days, it has been used to assess a great number of genotoxic/antigenotoxic agents, which contributes to its increasing application in environmental monitorin...

Effect of abscisic acid (ABA) and polyamines (PAs) [putrescine (Put), spermidine (Spd) and spermine (Spm)] on mitosis in root tips of A. cepa was studied. Treatment with ABA (0.1 to 100 microM) for 24 hr suppressed the mitosis, measured as mitotic index (MI), in a concentration-dependent manner with approx. 50% suppression at 10 microM of ABA. Treatment with different PAs (1 to 100 microM) had ...