نتایج جستجو برای: alleles
تعداد نتایج: 67556 فیلتر نتایج به سال:
Statistical methodology for testing the Hardy–Weinberg equilibrium at X chromosomal variants has recently experienced considerable development. Up to a few years ago, was basically done by applying autosomal test procedures females only. At present, male alleles can be taken into account in asymptotic and exact both bi- multiallelic case. However, current multiple rely on classical full enumera...
recognizing of genetic diversity and genetic potential of each plant species is necessary and essential before any works on breeding program. genetic diversity among five populations of walnut (juglans regia l.) was studied using 11 ssr markers. the marker system produced 77 alleles in a range size of 176-275 bps. the minimum (2) and maximum (11) numbers of alleles were related to genetic locus...
background: myasthenia gravis is an autoimmune disorder of neuromuscular junction characterized by skeletal muscle weakness and fatigability. different genes may control the induction and clinical presentation of this disease. various hla alleles are reported as predisposing or protective genetic elements in myasthenia gravis. objective: the aim of this study was to investigate the probable ass...
The common fig (Ficus carica L.), one of the most important fruit species, belongs to Moraceae family and is widely distributed in Iran. In this study, genetic variations among some genotypes of common fig collected from six different regions of Ilam province (Iran) were evaluated based on RAPD and ISSR markers. A total of 73 and 29 alleles were produced by 14 RAPD (with their sizes ranging fro...
Background and Objective: The outcome of hepatitis B virus (HBV) infection may be influenced by host factors like Human Leukocyte Antigen (HLA). We have investigated HLA-A and DRB1 alleles in patients with persistent hepatitis B infection compared to subjects who had spontaneously recovered from HBV infection. To complete the findings of this study we performed another survey in certain HLA ...
Background and Objective: Phenylketonuria (PKU) is a metabolic disorder that is caused by mutations in the phenylalanine hydroxylase (PAH) gene. The multiplicity of mutations in the PAH gene of PKU leads to the cases, in which the pathogenic mutation cannot be detected. In these cases, the variable number of tandem repeat (VNTR), which is the polymorphic marker associated with the PAH gene, is ...
Background: The length of GT-repeats polymorphic region in the promoter of human Heme oxygenase-1 gene (HO-1) alters the level of its transcriptional activity in response to oxidative stresses. Decreased level of HO-1 protein in the seminal plasma has been reported to be associated with oligospermia and azoospermia in male infertility. This is the first study to investigate the association betw...
Background: Based on the reports, high frequency of special alleles of HLA class II genes might be associated with susceptibility to or protective from a particular cancer. These alleles might vary depending on the geographical region. Here we investigate the association between alleles of HLA class II genes and breast cancer in Iranian women.Methods: 100 patients with pathologically proved bre...
Using SSR, a molecular marker, this study aimed to evaluate the genetic diversity and relationship among 55 herbaceous peony (Paeonia lactiflora Pall.) cultivars belonging Lactiflora, Hybrid Itoh Groups lay foundation for classification of cultivars, as well background analysis breeding new cultivars. Our results show that 86 alleles, 76 which were polymorphic, obtained by screening 13 pairs po...
Abstract Mucopolysaccharidoses are lysosomal storage diseases characterized by the excessive accumulation of glycosaminoglycan sulfate in organs and tissues. To determine population allelic frequency MPS complex variants a without clinical molecular diagnosis MPS. An observational descriptive study was carried out where presents IDUA, IDS, SGSH, NAGLU, HGSNAT, GNS, GALNS, GLB1, ARSB, GUSB, HYAL...
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