Elevated DNA repair processes represent resistance mechanisms to the treatment of malignancies with alkylating agents. Recently, the cell cycle checkpoint abrogator, UCN-01, was reported to inhibit nucleotide excision repair in cell-free systems. We hypothesized that if UCN-01 was combined with DNA-damaging agents, UCN-01 might inhibit the damage repair processes, thereby enhancing cytotoxicity...

1. The fall in chlorine concentration of Dakin's hypochlorite solution is more rapid in contact with necrotic than in contact with normal tissue. 2. The fall in chlorine concentration of chloramine-T solution is very slight when applied to necrotic tissue and is negligible when applied to normal tissue. 3. The action of the hypochlorite solution on tissue results in the separation of particles ...

zeolites due to their structures can be used as molecular sieves for purification of materials and solutions. zeolites with phi and sod structure are so common and applicable for this purpose. hydroxy sodalite and phillipsite are the more abundant members of zeolites which display good selectivity for very small molecules and some ions such as sr, pb, zn, cu and rb. there is not any pure natura...

Polysaccharide from the seeds of Plantago asiatica L. has many bioactivities, but few papers report on the structural and rheological characteristics of the alkaline extract. The alkaline extracted polysaccharide was prepared from seeds of P. asiatica L. and named herein as alkaline extracted polysaccharide from seeds of P. asiatica L. (PLAP). Its structural and rheological properties were char...

This article is dedicated to the identification of perspective areas for disposal ash and slag waste from thermal power plants, namely generated at TPP-1 in Pavlodar. The composition was considered by methods X-ray fluorescence phase analysis order identify most suitable area their further use. Based on data obtained, it proposed use extraction precious metals, such as aluminum iron, alkaline l...

Ceria has proven to be an excellent ion-transport and ion-exchange material when used in polycrystalline form with a high-concentration of aliovalent doped cations. Despite its widespread application, the impact atomic-scale defects this are scarcely studied poorly understood. In article, using first-principles simulations, we provide fundamental understanding atomic-structure, thermodynamic st...

A simple and rapid procedure for SO2 determination in air was developed by using a flow injection analysis (FIA) system coupled with a 3-hole chromatomembrane cell (CMC). The CMC was applied for the on-line collection/concentration of SO2 from air into a solution of 2 g l(-1) triethanolamine (TEA) solution as an absorbing solution: SO2 was converted to SO3(2-) in the alkaline absorbing solution...