Su X, Looney MR, Gupta N, Matthay MA. Receptor for advanced glycation end-products (RAGE) is an indicator of direct lung injury in models of experimental lung injury. Am J Physiol Lung Cell Mol Physiol 297: L1–L5, 2009. First published May 1, 2009; doi:10.1152/ajplung.90546.2008.—Receptor for advanced glycation end-products (RAGE) is a marker of alveolar type I cells and is elevated in the pulm...

BACKGROUND Few emergency department (ED) evaluations on acute lung injury (ALI) have been carried out; hence, we sought to describe a cohort of hospitalized ED patients at risk for ALI development. METHODS Patients presenting to the ED with at least one predisposing condition to ALI were included in this study, a subgroup analysis of a multicenter observational cohort study (USCIITG-LIPS 1). ...

BACKGROUND Differential diagnosis between acute cardiogenic pulmonary edema (APE) and acute lung injury/acute respiratory distress syndrome (ALI/ARDS) may often be difficult. We evaluated the ability of chest sonography in the identification of characteristic pleuropulmonary signs useful in the diagnosis of ALI/ARDS and APE. METHODS Chest sonography was performed on admission to the intensive...

BACKGROUND Acute lung injury (ALI) induced by cardiopulmonary bypass (CPB, CPB-ALI) is a common and serious complication after cardiac surgery. And infants and young children are more prone to CPB-ALI. The purpose of this study was to investigate the perioperative changes of plasma gelsolin (pGSN) in patients below 3 years of age with cardiac surgeries and CPB, and determine whether pGSN are as...

Acute lung injury (ALI) remains a major cause of morbidity and mortality in critically ill patients. Despite improved understanding of the pathogenesis of ALI, supportive care with a lung protective strategy of mechanical ventilation remains the only treatment with a proven survival advantage. Most clinical trials in ALI have targeted mechanically ventilated patients. Past trials of pharmacolog...

Acute lung injury (ALI) is a critical illness syndrome with a mortality rate of 25-40%. Despite recent advances of our understanding of the pathophysiology of ALI, no pharmacologic therapies have been proven effective. The key pathogenesis of ALI is the activation of the coagulation cascade and impaired fibrinolysis, resulting in extensive fibrin and hyaline membrane deposition. Activated prote...

We solve the integral equation describing the propagation of light in an isothermal plane-parallel atmosphere of optical thickness τ∗, adopting a uniform thermalization parameter ǫ. The solution given by the ALI method, widely used in the field of stellar atmospheres modelling, is compared to the exact solution. Graphs are given that illustrate the accuracy of the ALI solution as a function of ...

A study of 50 sugar maples {Acer saccharum) along Gates Mills Boulevard in Gates Mills, Ohio, showed that a tree's sap-sugar concentration tended to increase with decreasing tree health and increasing soil salt concentration. Relative tree health was determined by growth ring analysis. Salt concentration in soil was determined by measuring soil extract conductivity. Extract conductivity correla...