نتایج جستجو برای: alfuzosin

تعداد نتایج: 166  

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2009
Rong Zhao Thomas J Raub Geri A Sawada Steven C Kasper James A Bacon Arlene S Bridges Gary M Pollack

Expression of breast cancer resistance protein (Bcrp) at the blood-brain barrier (BBB) has been revealed recently. To investigate comprehensively the potential role of Bcrp at the murine BBB, a chemically diverse set of model compounds (cimetidine, alfuzosin, dipyridamole, and LY2228820) was evaluated using a multiexperimental design. Bcrp1 stably transfected MDCKII cell monolayer transport stu...

2012
Woo Heon Cha Jae Duck Choi Ki Ho Kim Young Jin Seo Kyungseop Lee

PURPOSE Typically in Korea, for a standard dose (0.4 mg) of tamsulosin, two low doses (0.2 mg) are administered. The aim of this study was to evaluate and compare the efficacy of tamsulosin (0.2 mg and 0.4 mg) and alfuzosin (10 mg) in the treatment of lower ureteral stones. MATERIALS AND METHODS A total of 141 patients presenting with a single 4- to 10-mm sized lower ureteral stone were rando...

2009
M. A. Roni G. Kibria R. Jalil

The aim of the present study was the determination of formulation factors and the in vitro evaluation of an extended release dosage form of a freely soluble weakly basic drug (alfuzosin hydrochloride). Binary mixer of one hydrophilic polymer (hydroxypropylmethylcellulose) and one directly compressible Eudragit (RS PO) was used in tablets prepared by direct compression. The amounts of both polym...

2012
D. Prasanthi P. K. Lakshmi

The objective of the present study is to explore the efficient chemical penetration enhancer among the various enhancers available in overcoming the stratum corneum barrier in transdermal delivery of Alfuzosin hydrochloride (AH). The different enhancers were incorporated in 2% Carbopol gel which was selected as a control and evaluated by in vitro diffusion studies through dialysis membrane and ...

2013
Hee Ju Cho Soon Cheol Shin Do Young Seo Dong Suk Min Jeong Man Cho Jung Yoon Kang Tag Keun Yoo

PURPOSE We evaluated the efficacy of alfuzosin for the treatment of ureteral calculi less than 10 mm in diameter after extracorporeal shock wave lithotripsy (ESWL). MATERIALS AND METHODS A randomized, single-blind clinical trial was performed prospectively by one physician between June 2010 and August 2011. A total of 84 patients with ureteral calculi 5 to 10 mm in diameter were divided into ...

Journal: :The journal of sexual medicine 2010
Somboon Leungwattanakij Damrongpun Watanachote Patra Noppakulsatit T Petchpaibuol Nopporn Choeypunt Thanasak Tongbai Teerawan Wanamkang Bunnakij Lojanapiwat Sompol Permpongkosol Anupan Tantiwong Chusak Pripatnanont Danaipan Akarasakul Somsak Kongwiwatanakul Ekarat Chotikawanich

INTRODUCTION Benign prostatic hyperplasia (BPH) is a common condition among elderly men. The aim of therapy is to improve lower urinary tract symptoms (LUTS) and quality of life (QoL) and to prevent complications. AIM The primary objective was to assess the effect on ejaculatory dysfunction (EjD) of 6 months treatment with alfuzosin (XATRAL) 10 mg once daily (OD) in men with LUTS suggestive o...

2017
Chikka Moga Siddaiah Manohar Mahadevappa Nagabhushana Vilvapathy Senguttuvan Karthikeyan Ramachandra Pudakalkatti Sanjay Ananth Janardhan Kamath Ramaiah Keshavamurthy

INTRODUCTION Currently alpha1-adrenoceptor blockers (AB) are widely used as first-line therapy to improve lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). We compared the efficacy and safety profile of tamsulosin, alfuzosin and silodosin in LUTS due to BPH. MATERIAL AND METHODS Consecutive consenting male patients (N = 269) undergoing medical management ...

Journal: :iranian journal of pharmaceutical sciences 0
monzurul amin roni department of pharmaceutical technology, faculty of pharmacy, university of dhaka, dhaka-1000, bangladesh golam kibria department of pharmaceutical technology, faculty of pharmacy, university of dhaka, dhaka-1000, bangladesh reza-ul jalil department of pharmaceutical technology, faculty of pharmacy, university of dhaka, dhaka-1000, bangladesh

extended release formulation of alfuzosin, an a-antagonist used for prostatic hypertrophy, is available in market. it is convenient for older patients to take only one tablet a day. marketed alfuzosin formulation is three layered geomatrix tablet that requires special facilities, high cost, more time and complex operation than normal direct compression formulation. therefore, a less complicated...

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