The present study was conducted to evaluate the ameliorating effect of 5-aminolevulinic acid (ALA) on physiological and biochemical changes of induced NaCl-salinity stress on in vitro shoot and callus cultured of red-fleshed apple. Shoot and callus segments of the red-flesh apple of Local Iranian genotype were cultured on MS medium containing different levels of NaCl (0, 30, 60 and 90 mM) and A...

Background: Cryopreservation of pre-antral follicles is a hopeful technique to preserve female fertility. The aim of the present study was to evaluate reactive oxygen species (ROS) and total antioxidant capacity (TAC) levels of mouse vitrified pre-antral follicles in the presence of alpha lipoic acid (ALA). Methods: Isolated pre-antral follicles (140–150 µm in diameter) were divided into vitrif...

Keratoacanthoma-like squamous cell carcinoma (KA-like SCC) is a malignant classification of KA. We report here case surgical combined with 5-aminolevulinic acid-photodynamic therapy (ALA-PDT) to treat KA-like SCC in an elderly male successful tumor removal. The resection was performed before ALA-PDT. One week later, the lesion site further treated 20% ALA for 3 h when it unknown whether resecte...

objective(s): to investigate the association of single nucleotide polymorphisms (snps) in the peroxisome proliferator-activated receptors gamma (pparg) with essential hypertension (eh) and additional role of gene– high-density lipoprotein cholesterol (hdl) interaction. materials and methods:a total of 1640 patients with eh (806 males, 834 females), with a mean age of 52.5±12.6 years, were selec...

compound of 5-aminolevulinic acid (5-ala) has herbicide behavior in high concentration. while, it acts as growth regulator at low concentrations and causes resistance to various stresses incluing cold and salibity. therefore the exogenous application of 5-aminolevulinic acid was investigated to induce cold stress tolerance in young soybean plants (glycine max l.). the experiment was conducted a...

Alpha-lipoic acid (ALA) is a naturally-occurring compound that has shown promising antioxidant and anti-inflammatory effects in experimental and human studies. The aim of this study was to assess the efficacy of ALA in the management of patients with diabetes mellitus (DM).We searched Medline (via PubMed), EBSCO, Scopus, and Web of Science for relevant randomized controlled trials. Data o...

bacterial penicillin-binding proteins and beta-lactamases. Antimicrob. Agents Chemother. 42(1), 1 17. [41] Davies, C., White, S.W., Nicholas, R.A. (2001). Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-Å resolution. J. Biol. Chem. 276(1), 616 623. [42] Nicola, G., Tomberg, J., Pratt, R.F., Nicholas, R.A., Davies, C. (2010). Crystal structures of coval...

Background: 5-aminolevulinic acid (5-ALA) has a poor penetrance of the skin with topical application, which reduces efficacy Photodynamic therapy (PDT). Sonophoresis involves use sound waves or ultrasonic energy to enhance transdermal delivery drugs. The purpose this study was investigate effects sonophoresis on penetration 5-ALA into skin. Methods: We calculatedin vitrotransdermal accumulation...