نتایج جستجو برای: akbari array saa

تعداد نتایج: 135800  

2015
Paulette A. Krishack Godfrey S. Getz Catherine A. Reardon

Background-—Atherosclerosis is a chronic inflammatory disorder, and several studies have demonstrated a positive association between plasma serum amyloid A (SAA) levels and cardiovascular disease risk. The aim of the study was to examine whether SAA has a role in atherogenesis, the underlying basis of most cardiovascular disease. Methods and Results-—Mice globally deficient in acute-phase isofo...

2015
Xue-Yan Zhang Ge Zhang Ying Jiang Dan Liu Man-Zhi Li Qian Zhong Shan-Qi Zeng Wan-Li Liu Mu-Sheng Zeng

BACKGROUND Elevated levels of serum C-reactive protein (CRP) have been reported to have prognostic significance in lung cancer patients. This study aimed to further identify CRP-bound components as prognostic markers for lung cancer and validate their prognostic value. METHODS CRP-bound components obtained from the serum samples from lung cancer patients or healthy controls were analyzed by d...

Journal: :Journal of molecular recognition : JMR 2015
Martyna Maszota Natalia Karska Marta Spodzieja Jerzy Ciarkowski Aleksandra S Kołodziejczyk Sylwia Rodziewicz-Motowidło Paulina Czaplewska

Serum amyloid A (SAA) is a multifunctional acute-phase protein whose concentration in serum increases markedly following a number of chronic inflammatory and neoplastic diseases. Prolonged high SAA level may give rise to reactive systemic amyloid A (AA) amyloidosis, where the N-terminal segment of SAA is deposited as amyloid fibrils. Besides, recently, well-documented association of SAA with hi...

2016
Kyra D Kingma Antonius N van der Linden Rudi M H Roumen

Background. Splenic artery aneurysm (SAA) is an uncommon and difficult diagnosis. SAA is more common in females. Only 20% of SAA is symptomatic and may present as a rupture. A ruptured SAA is associated with a 25% mortality rate. Case Presentation. We present a case of a male patient with a bleeding SAA that rapidly increased in size. Distal coiling was technically impossible and despite proxim...

Journal: :The Journal of Experimental Medicine 1979
J D Sipe S N Vogel J L Ryan K P McAdam D L Rosenstreich

The mechanism by which LPS stimulates an acute phase serum amyloid A (SAA) response in C3H mice has been studied. A factor (SAA inducer) appears in the blood of C3H/HeN (lipopolysaccharide [LPS]-sensitive) mice approximately 1 h after administration of LPS, which, when passively administered, can induce C3H/HeJ mice to produce SAA although they are resistant to the LPS itself. SAA inducer has b...

2015
Katja Lakota Mary Carns Sofia Podlusky Katjusa Mrak-Poljsak Monique Hinchcliff Jungwha Lee Matija Tomsic Snezna Sodin-Semrl John Varga

Inflammation in systemic sclerosis (SSc) is a prominent, but incompletely characterized feature in early stages of the disease. The goal of these studies was to determine the circulating levels, clinical correlates and biological effects of the acute phase protein serum amyloid A (SAA), a marker of inflammation, in patients with SSc. Circulating levels of SAA were determined by multiplex assays...

Journal: :The Journal of clinical investigation 1977
M D Benson M A Scheinberg T Shirahama E S Cathcart M Skinner

Serum amyloid protein A (SAA), the precursor of secondary amyloid protein, is elevated in chronic diseases which are associated with an increased incidence of amyloid. However, SAA is also elevated in acute bacterial and viral infections and somes forms of cancer. The murine model of casein-induced amyloidosis was studied to determine the relationship between SAA production and amyloid depositi...

2014
Ting Wang Shu-chong Mei Rong Fu Hua-quan Wang Zong-hong Shao

Abnormal telomere attrition has been found to be closely related to patients with SAA in recent years. To identify the incidence of telomere attrition in SAA patients and investigate the relationship of telomere length with clinical parameters, SAA patients (n=27) and healthy controls (n=15) were enrolled in this study. Telomere length of PWBCs was significantly shorter in SAA patients than in ...

Journal: :Journal of lipid research 1985
P M Clifton A M Mackinnon P J Barter

The acute phase reactant serum amyloid A protein (SAA) circulates in plasma as a constituent of high density lipoproteins (HDL). Advantage has been taken of the induction of SAA in human subjects with myocardial infarction to study the effect of SAA on the physical and chemical properties of HDL. HDL were isolated by sequential ultracentrifugation and assayed for chemical composition. Apolipopr...

2015
Gerald F. Giesbrecht Douglas A. Granger Tavis Campbell Bonnie Kaplan

Diurnal patterns of salivary alpha amylase (sAA) in pregnant women have not previously been described. The current study employed ecological momentary assessment to examine the association between the diurnal sAA, obstetric history, maternal demographics, and mood during pregnancy. Saliva was self-collected by 83 pregnant women (89% White, age 25.3-43.0 years; mean gestational age 21.9 weeks, r...

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