OBJECTIVE Little is known about the interaction between human papillomavirus (HPV) and HIV. This study aimed to explore the association of oncogenic (high risk) and nononcogenic (low risk) HPV with HIV incidence. METHODS We used 1683 urethral swabs collected at the last follow-up visit of a male circumcision trial conducted in Orange Farm (South Africa). Swabs analyses and HPV genotyping were...

Whereas excessive alcohol consumption increases liver disease incidence and mortality, evidence on the risk associated with specific drinking patterns is emerging. We assessed impact of binge mortality in Swiss HIV Cohort Study. All participants follow-up between 2013 2020 were categorized into one four pattern groups: “abstinence”, “non-hazardous drinking”, “hazardous but not drinking” (Alcoho...

OBJECTIVES HIV-positive people have increased risk of infection-related malignancies (IRMs) and infection-unrelated malignancies (IURMs). The aim of the study was to determine the impact of aging on future IRM and IURM incidence. METHODS People enrolled in EuroSIDA and followed from the latest of the first visit or 1 January 2001 until the last visit or death were included in the study. Poiss...

BACKGROUND: Approximately 10% of incident TB cases worldwide are attributable to alcohol. However, evidence associating alcohol with unfavorable treatment outcomes is weak. METHODS: We prospectively evaluated men (≥18 years) pulmonary in India for up 24 months investigate the association between use and outcomes. Unhealthy was defined as a score ≥4 on Alcohol Use Disorders Identification Test-C...

Background. We studied the safety and reactogenicity SARS-CoV-2 mRNA vaccines in transplant recipients because immunosuppressed patients were excluded from vaccine trials. Methods. US recruited into this prospective cohort study through social media; those who completed full series between December 9, 2020 March 1, 2021 included. collected demographics, medical history, information within 7 d a...

This study examined the multilevel correlates of childhood mortality among women (aged 15–49 years) in Nigeria using pooled data from 2003, 2008 and 2018 Demographic Health Surveys. considered 25,685 who stated that they never lived outside their communities. Descriptive regression analyses were performed. About 38% reported losing at least a child. The individual-level age, age first birth, ye...

OBJECTIVE This study compared the clinical and economic benefits associated with dual-goal achievement, glycated hemoglobin (HbA1c)<7% (53 mmol/mol) and LDL cholesterol (LDL-C)<100 mg/dL, with achievement of only the LDL-C goal or only the HbA1c goal in veterans with type 2 diabetes mellitus (T2DM). RESEARCH DESIGN AND METHODS This retrospective cohort analysis evaluated electronic medical re...

BACKGROUND The optimal duration of preventive therapy for tuberculosis (TB) among HIV-infected persons in TB-endemic countries is unknown. METHODS An open-label randomized clinical trial was performed and analyzed for equivalence. Seven hundred and twelve HIV-infected, ART-naïve patients without active TB were randomized to receive either ethambutol 800 mg and isoniazid 300 mg daily for six-m...