INTRODUCTION The value of argyrophilic nucleolar organizer regions (AgNORs) to predict survival in patients with ovarian cancer has not been clearly explained yet. The aim of study was to assess the value of analysis of the mean number of AgNORs per nucleus (mAgNOR) and mean percentage of nuclei with five or more AgNORs per nucleus (pAgNOR) in the prediction of disease-free survival (DFS) and o...

Author investigated the cell infiltrative activity, cell growth and cell proliferative activity of flat type colorectal cancer. Tissue specimens were obtained by surgery. These specimens were examined in expression of CD44 for the evaluation of cell infiltrative activity and Ki67 for growing cell, and then double-staining for AgNORs and Ki67 was performed to evaluate proliferative activity in g...

Background: Cell proliferation is an important factor in the prognosis of malignant neoplasia. The number of argyrophilic nucleolar organizer regions (AgNORs) per cell has been considered as an indicator of the cellular proliferative activity. A study is carried out to examine whether AgNOR numbers relate to the growth rate in squamous cell carcinoma (SCC) of the oral cavity. Aim: To verify the...

AIM To evaluate the interphase ribosomal RNA cistron activity of cardiomyocytes in surgical patients with chronic ischaemic heart disease by means of the nucleolar organiser region silver staining (AgNOR) technique. METHODS Nucleoli were investigated in myocardial samples obtained from 46 patients with chronic ischaemic heart disease before, during, and soon after cardioplegia ischaemia. Cryo...

Karyotypes and chromosomal characteristics of both minor and major rDNAs in four fish species known popularly as "lambaris", namely Astyanaxabramis (Jenyns, 1842), Astyanaxasuncionensis Géry, 1972, Astyanaxcorrentinus (Holmberg, 1891) and Astyanax sp. collected from downstream of the Iguassu Falls (Middle Paraná River basin), preservation area of the Iguassu National Park, were analyzed by conv...

Hepatocellular carcinoma (HCC) is among the most common malignancies worldwide, particularly in South and South East Asia. Unfortunately due to lack of appropriate facilities and awareness only limited information is available about its early diagnosis. Aim of the present study was to determine the efficacy of p53 by immunohistochemistry and Argyrophilicnucleolar organizer regions (AgNORs) in d...

AIM To evaluate the morphofunctional characteristics of lymph node cells from patients with Hodgkin's disease by measuring silver stained nucleolar organiser regions (AgNORs). METHODS Nucleoli in Hodgkin's and Reed-Sternberg (HRS) cells, lymphocytes and prolymphocytes were investigated in cytological smears and histological sections of lymph nodes from 32 patients with Hodgkin's disease, and ...

OBJECTIVE To evaluate the changes induced in silver-stained nucleolar organizer regions (AgNORs) by the first fraction of a radiotherapy protocol for gynecologic cancer on exfoliated cytologic samples to predict the therapeutic success of the full protocol. STUDY DESIGN Thirteen gynecologic cancer patients who were scheduled for radiotherapy were included in the study. Cell smears were taken ...