نتایج جستجو برای: aging related alterations of dmn

تعداد نتایج: 21259824  

2015
Megan M. Herting Kristina A. Uban Paige L. Williams Prapti Gautam Yanling Huo Kathleen Malee Ram Yogev John Csernansky Lei Wang Sharon Nichols Russell Van Dyke Elizabeth R. Sowell Kirsten Donald.

Youth with perinatally acquired human immunodeficiency virus (PHIV+) survive longer with combination antiretroviral therapy, but remain at risk for poor cognitive outcomes. We evaluated whether markers of HIV disease severity relate to default mode resting-state functional connectivity in PHIV+ youth. We conducted resting-state functional neuroimaging and cognitive testing in a subset of 40 PHI...

2013
Andrei Manoliu Valentin Riedl Anselm Doll Josef Georg Bäuml Mark Mühlau Dirk Schwerthöffer Martin Scherr Claus Zimmer Hans Förstl Josef Bäuml Afra M. Wohlschläger Kathrin Koch Christian Sorg

Schizophrenia is characterized by aberrant intrinsic functional connectivity (iFC) within and between intrinsic connectivity networks (ICNs), including the Default Mode- (DMN), Salience- (SN), and Central Executive Network (CEN). The anterior insula (AI) of the SN has been demonstrated to modulate DMN/CEN interactions. Recently, we found that the dependence of DMN/CEN interactions on SN's right...

2016
Soo Hyun Joo Hyun Kook Lim Chang Uk Lee

Normal aging and to a greater degree degenerative brain diseases such as Alzheimer's disease (AD), cause changes in the brain's structure and function. Degenerative changes in brain structure and decline in its function are associated with declines in cognitive ability. Early detection of AD is a key priority in dementia services and research. However, depending on the disease progression, neur...

Journal: :Psychological medicine 2014
F Sambataro N D Wolf M Pennuto N Vasic R C Wolf

BACKGROUND Major depressive disorder (MDD) is characterized by alterations in brain function that are identifiable also during the brain's 'resting state'. One functional network that is disrupted in this disorder is the default mode network (DMN), a set of large-scale connected brain regions that oscillate with low-frequency fluctuations and are more active during rest relative to a goal-direc...

2017
Bernadet L. Klaassens Joop M. A. van Gerven Jeroen van der Grond Frank de Vos Christiane Möller Serge A. R. B. Rombouts

Both normal aging and Alzheimer's disease (AD) have been associated with a reduction in functional brain connectivity. It is unknown how connectivity patterns due to aging and AD compare. Here, we investigate functional brain connectivity in 12 young adults (mean age 22.8 ± 2.8), 12 older adults (mean age 73.1 ± 5.2) and 12 AD patients (mean age 74.0 ± 5.2; mean MMSE 22.3 ± 2.5). Participants w...

2011
Katell Mevel Gaël Chételat Francis Eustache Béatrice Desgranges

In the past decade, a "default mode network" (DMN) has been highlighted in neuroimaging studies as a set of brain regions showing increased activity in task-free state compared to cognitively demanding task, and synchronized activity at rest. Changes within this network have been described in healthy aging as well as in Alzheimer's disease (AD) and populations at risk for AD, that is, amnestic ...

2016
Nicholas Fallon Yee Chiu Turo Nurmikko Andrej Stancak

Fibromyalgia syndrome (FMS) patients show altered connectivity with the network maintaining ongoing resting brain activity, known as the default mode network (DMN). The connectivity patterns of DMN with the rest of the brain in FMS patients are poorly understood. This study employed seed-based functional connectivity analysis to investigate resting-state functional connectivity with DMN structu...

Journal: :The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2009

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده علوم 1374

we have devided the thesis in to five chapters. the first recollects facts from purely algebraic theory of jordan algebras and also basic properties of jb and jb* - algebras which are needed in the sequel. in the second chapter we extend to jb* - algebras, a classical result due to cleveland [8]. this result shows shows the weakness of jb* - norm topology on a jb* - algebera. in chapter three, ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده ادبیات و علوم انسانی 1388

the purpose of this study was to investigate how english language teachers in mashhad who teach students in the pre-university cycle perceived the impact of the efltee on their teaching. the target population was nearly all pre-university english language teachers in seven districts of mashhad in the scholastic year 2008/2009. a survey questionnaire which consisted of (36) likert type items, wa...

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