Latar belakang: empat belas koma tiga persentase dari masyarakat Indonesia mengalami penyakit periodonsium. Bakteri Aggregatibacter actinomycetemcomitans adalah bakteri yang dapat ditemukan pada 90% penderita periodontitis agresif. ini termasuk dalam golongan gram-negatif merupakan penyebab utama Nanas (Ananas comosus) tanaman buah mengandung enzim bromelin. Enzim berpotensi memiliki sifat anti...

Background/Aim: This study aimed to evaluate the effects of Lactobacillus reuteri lozenges as an adjunctive therapeutic agent in combination with scaling and root planning a randomized, clinical trial volunteers periodontitis stage IV. Material Methods: The included 40 patients diagnosed divided into 2 groups 20 by random sample method. first group used after nonsurgical periodontal therapy for...

This study examined in vivo and in vitro colonization by Aggregatibacter actinomycetemcomitans, an organism highly associated with aggressive periodontitis. Thirteen volunteers (5 were A. actinomycetemcomitans positive for buccal epithelial cells [BECs] and teeth, 5 were A. actinomycetemcomitans positive for teeth only, and 3 were A. actinomycetemcomitans-negative controls) had two mandibular s...

mitogen-activated protein kinase signaling in receptor activator of nuclear factorjB ligand expression and osteoclastogenesis induction by Aggregatibacter actinomycetemcomitans and Escherichia coli lipopolysaccharide C. Rossa, Jr, M. Liu, K. L. Kirkwood Department of Diagnosis and Surgery, School of Dentistry at Araraquara, State University of Sao Paulo (UNESP), Araraquara, SP, Brazil and Depar...

Infections caused by multiple organisms, or polymicrobial infections, are likely more common than is broadly appreciated. Interaction among microbial communities (and with their host) can change the infection landscape by subverting immunity, providing nutrients and inhibiting competing microbes. Stacy et al. (A. Stacy, D. Fleming, R. J. Lamont, K. P. Rumbaugh, and M. Whiteley, mBio 7:e00782-16...

Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins such as cytolethal distending toxin (CDT) and leukotoxin (LtxA) into human host cells and to act as triggers of innate immunity upon carriage of ...