We have studied the influence of the peripheral vasodilator hydralazine (HDZ) on the vasculature and blood perfusion of two members of a series of subcutaneous murine adenocarcinomata of the colon (MAC tumours), and the influence of HDZ on the efficacy and/or toxicity of TCNU and melphalan.

In regulation of exposures to hazardous environmental agents, epidemiologic evidence is especially important in defining human risk estimates. The process of developing appropriate regulations is complex, however, and depends on many considerations beyond those established to a high degree of scientific certainty. Thus the needs of regulatory agencies are involved in the way epidemiologic data ...

In the eld of multiagent systems, belonging to the more general area of Distributed Arti cial Intelligence (DAI), it is important to conceive a multiagent system as an unique machine, called agency. The conception of agency as an unitary machine, which derives from the work of Minsky [8], has the interesting role of focusing some of the critical problems involving the agency machine in general....

This paper presents a survey and overview of the evaluation of infrastructure regulation and regulatory agencies. It covers the development of ex ante and ex post evaluation based on costbenefit analysis and the application of these methods to regulation in the UK, the European Union and the USA. Much of the work in this area has been on infrastructure regulation in developing countries. The pa...

September1998 x The authors are grateful to Tim Baldenius, Christian Laux and Xiao-Jun Zhang for helpful comments and suggestions.

MEDICAL CHARGE OF POLITICAL AGENCIES. Tiie classification of the Civil Surgeoncies under the direct control of the Foreign Office, which appeared in the Gazette of India of the 12th September, has taken us by surprise. We knew, from sad experience in other cases, that the number of first-class stations was likely to be very small, but we certainly were not prepared to see only Indore and Rajpoo...

Background: Diagnosis of tuberculosis (TB) remains problematic despite many new advanced diagnostic methods. A reliable and rapid diagnostic test, which could be performed in any standard pathology laboratory, would help to obtain definitive early diagnoses of TB. In the present study we describe a prospective evaluation for demonstrating Antigen (Ag) 85 complex in the sera from TB patients. Me...

municipal solid waste management (mswm) has become the greatest problem facing many urban and semi-urban areas in nigeria, although to varying degrees. this study suggests the various steps and approaches to combat the menace in akure in the southwest zone of nigeria. such approaches include creation of special agencies for the collection, recycling and conversion of municipal solid waste (msw)...