STUDY QUESTION
Is the activity of sirtuin 3 (SIRT3) altered in granulosa and cumulus cells from young women with reduced ovarian reserve or women of advanced maternal age?
SUMMARY ANSWER
SIRT3 mRNA and active protein in granulosa and cumulus cells were decreased in women with reduced ovarian reserve and advanced maternal age.
WHAT IS KNOWN ALREADY
Young women with reduced ovarian reserve or...