Mitochondrial diseases are polymorphic entities which may affect many organs and systems. Skeletal muscle involvement is frequent in the context of systemic mitochondrial disease, but adult-onset pure mitochondrial myopathy appears to be rare. We report 3 patients with progressive skeletal mitochondrial myopathy starting in adult age. In all cases, the proximal myopathy was the only clinical fe...

92 Ann Dermatol Received October 25, 2013, Revised January 16, 2014, Accepted for publication February 1, 2014 Corresponding author: Bong Seok Shin, Department of Dermatology, Chosun University Hospital, 365 Pilmun-daero, Dong-gu, Gwangju 501-717, Korea. Tel: 82-62-220-3130, Fax: 82-62-222-3215, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creati...

Six cases are described of muscle weakness and wasting of scapuloperoneal distribution with an onset in early adult or middle life and a relatively benign progression. One case also showed mild facial weakness. Four cases were probably sporadic but in two, a mother and daughter, autosomal dominant inheritance was likely. Electromyographic studies demonstrated myopathic features in all, and this...

The adult onset Still’s disease is a rare affection characterised by occurrence of fever, arthralgia or arthritis and evanescent cutaneous eruption. Multiple other systemic lesions make the diagnosis more difficult. Several diagnostic criteria were formulated to confirm this disease. The physiopathology of the adult onset Still’s disease is not well elucidated. However, several studies based on...

Sir, Adult Onset StillÊs Disease (AOSD) was reported first by Baywaters in 1976 with clinical features identical to those of Juvenile Rheumatoid Arthritis (JRA). Studies from France, Japan and India3 comparing and analyzing clinical features, course and prognosis of JRA and AOSD are basically identical. The pathogenesis and treatment are also the same. It seems therefore reasonable to consider ...

We conducted a retrospective observational study to describe a cohort and identify the prognostic factors in adult-onset Still disease (AOSD). Patients enrolled in this retrospective chart review fulfilled either Yamaguchi or Fautrel criteria. Candidate variables were analyzed with logistic unadjusted and adjusted regression models. Fifty-seven patients were seen in the internal medicine (75%) ...