Quantum dots are new types of fluorescent materials for biological labeling. As a result, QDs toxicity study is an essential requirement for future clinical applications. Therefore, the cytotoxic CdSe:ZnS quantum dots effects on some organs in mice are presented in this study. In this work, 10, 20 and 40 mg/kg doses of CdSe:ZnS quantum dots were injected to 32 adult male mice. Structural and op...

The relationship between the immunoglobulin (Ig) nucleotide sequence and the ability of a B cell to develop into a malignant cell was studied in a subset of B cells, B-1 cells. B-1 cells become malignant in chronic lymphocytic leukemia (CLL) and are responsible for the production of "natural autoanti‌bodies". The autoimmune NZB mouse has been known as a human malignancy and CLL model, be‌cause ...

ABSTRACT We examined whether peripheral leukocytes of mice derived from in vitro αMEM-cultured embryos and exhibiting type 2 diabetes had higher expression inflammatory-related genes associated with the development atherosclerosis. Also, we impact a barley diet on inflammatory gene expression. Adult were produced by embryo transfer, after culturing two-cell for 48 h either α minimal essential m...

Introduction: Results of several studies on different effects of electromagnetic waves reveal that change of field intensity, even milli tesla has various biological effects, therefore investigation on electromagnetic effects can be done in very wide range. In this research, amount of these effects on biomass, thymus, testis and therapeutic role of vitamin C in...

Immune-defective and immunologically normal F1 mice derived from the CBA/N strain were used to study the influence of anti-endotoxin antibody on the lethal effects of endotoxin. Immune-defective F1 male mice were unable to make specific responses to purified preparations of E. coli O111:B4 endotoxin, whereas their immunologically normal F1 female littermates made excellent responses. The abilit...

noise is considered as one of the harmful factors at industrial environments. it affects human health in different aspects including harmful influences on auditory, vision, neurological and psychiatric systems, hormones, physiological and mental systems. paying attention to the importance of hormonal effects on human body seems to possess crucial importance. the aim of the present study is to i...

Acetaminophen (APAP) overdose induces acute liver injury. The aim of the present study was to analyze the difference of susceptibility between immature and adult mice to APAP-induced acute liver injury. Weanling immature and adult mice were injected with APAP (300 mg/kg). As expected, immature mice were more susceptible than adult mice to APAP-induced acute liver injury. APAP-evoked hepatic c-J...