Adsorption of monovalent and multivalent cat-and anions on a deoxyribose nucleic acid (DNA) molecule from a salt solution is investigated by computer simulation. The ions are modelled as charged hard spheres, the DNA molecule as a point charge pattern following the double-helical phosphate strands. The geometrical shape of the DNA molecules is modelled on different levels ranging from a simple ...

Abstract Background and Aims The role of complement in focal segmental glomerulosclerosis (FSGS) is an area interest C4d staining could indicate related renal damage. We investigated detailed properties native kidney biopsies possible relation to clinical features. Method retrospectively evaluated the 114 patients diagnosed with FSGS within last 15 years. expressions examined glomeruli (mesangi...

The purpose of work is to evaluate the 4-chlorophenol (CP) adsorption capacity brown coal activated carbons (ACs) prepared at different temperature KOH activation. ACs were obtained in three stages: 1) impregnation with a solution, 2) heating (4 deg/min) argon given t (400-800°C) and exposure for 1 h, 3) cooling, washing from KOH, drying. samples are designated as AC(t). Based on N2 adsorption-...

BACKGROUND Exon skipping oligonucleotides (ESOs) of 2'O-Methyl (2'OMe) and morpholino chemistry have been shown to restore dystrophin expression in muscle fibers from the mdx mouse, and are currently being tested in phase I clinical trials for Duchenne Muscular Dystrophy (DMD). However, ESOs remain limited in their effectiveness because of an inadequate delivery profile. Synthetic cationic copo...

We propose a scheme to measure the mass of a single particle using the nonlinear response of a 2D nanoresonator with degenerate eigenmodes. Using numerical and analytical calculations, we show that by driving a square graphene nanoresonator into the nonlinear regime, simultaneous determination of the mass and position of an added particle is possible. Moreover, this scheme only requires measure...

Environmental electromagnetic fi elds are nowadays available in all environments today. These areas affect the biological system. Controlled interactions with elecrtomagnetic fi elds can have positive effects when unrestricted interactions have negative effects. Uncontrolled exposure to low-frequency electromagnetic fi elds can cause adverse effects such as signal transduction in cells and tiss...