Extensive evidence demonstrates functional interactions between the adrenergic and opioid systems in a diversity of tissues and organs. While some effects are due to receptor and second messenger cross-talk, recent research has revealed an extracellular, allosteric opioid binding site on adrenergic receptors that enhances adrenergic activity and its duration. The present research addresses whet...

introduction: feverfew (tanacetum parthenium) (t.p.) is widely used in folk medicine to treat many diseases. we reported the analgesic effect of t.p. flower and leaf previously. present study is designed to find the mechanism underlying the anti-nociceptive effect of the aqueous extract of t.p. flower. method: based on our previous study, the dose 50 mg/kg i.p. of the t.p. aqueous extract had a...

statement of the problem: various researchers have suggested the use of β2-adrenergic receptor antagonists in prevention or treatment of bone resorption. purpose: this study aimed to evaluate the effect of β2-adrenergic receptor antagonists on number of osteoclasts and osteoblasts involved in the healing of extraction socket of maxillary first molar in rats. materials and method: maxillary firs...

I N 1964 Oj-adrenergic receptors were first described pharmacologically using the in vitro melanocyte granule dispersion technique in Rana pipiens. The goal of these studies was to assess the intrinsic activity on o^-adrenergic receptors of methyldopa's neurotransmitter metabolites and other catecholamines. Publication of this description was delayed for 13 years, 1 until the evidence for a rec...

Catecholamine, histamine, and adenosine-mediated accumulations of radioactive cyclic AMP were assessed in adenine-labeled slices from eight rat brain regions. 2-Fluoronorepinephrine, a selective beta-adrenergic agonist, elicited an an accumulation of cyclic AMP in cerebral cortex, cerebellum, hippocampus, striatum, superior colliculi, thalamus, hypothalamus, and medulla-pons. In cerebral cortex...

I N 1964 Oj-adrenergic receptors were first described pharmacologically using the in vitro melanocyte granule dispersion technique in Rana pipiens. The goal of these studies was to assess the intrinsic activity on o^-adrenergic receptors of methyldopa's neurotransmitter metabolites and other catecholamines. Publication of this description was delayed for 13 years, 1 until the evidence for a rec...

The role of adrenergic agents in augmenting proximal tubular salt and water flux, was studied in a preparation of freshly isolated rabbit renal proximal tubular cells in suspension. Norepinephrine (NE, 10(-5) M) increased sodium influx (JNa) 60 +/- 5% above control value. The alpha adrenergic antagonist, phentolamine (10(-5) M), inhibited the NE-induced enhanced JNa by 90 +/- 2%, while the beta...

1 Construction of Libraries for Isolation of Adrenergic Receptor Genes Margaret A. Scofield, Jean D. Deupree, and David B. Bylund ........ 3 2 Isolation of Adrenergic Receptor Genes Margaret A. Scofield, Jean D. Deupree, and David B. Bylund ...... 37 3 Analyses of Adrenergic Receptor Sequences Jean D. Deupree, Margaret A. Scofield, and David B. Bylund ...... 53 4 Polymerase Chain Reaction Scree...

In mammals, the roles of liver and skeletal muscle glycogen in adrenaline-induced hyperglycaemia are well known. However, amphibians, there is limited information on relative contribution hyperglycaemia. This study investigated effects adrenaline blood glucose, plasma lactate, liverand role adrenergic receptors common African toad, bufo regularis. One hundred twenty-five adult toads (70-100g) b...

Objective: Valeriana (V) wallichii DC is found among the ground flora of Himalayan regions and used as herbal medicine for CNS disorders in Indian systems medicine. In study, aimed to investigation involvement neuro-chemical-systems V. induced antidepressant effects mice.
 Methods: The activity aqueous alcoholic extracts was measured by using Forced Swim Test Tail Suspension mice, whereas ...