نتایج جستجو برای: admat aysmetric dimethylarginine

تعداد نتایج: 1925  

2005
HANNU PÄIVÄ Terho Lehtimäki Reijo Laaksonen Tomi Laitinen

5 TIIVISTELMÄ 7 CONTENTS 8 ABBREVIATIONS 10 LIST OF ORIGINAL PUBLICATIONS 1

2010
Felix Fleissner Virginija Jazbutyte Jan Fiedler Shashi K. Gupta Xiaoke Yin Qingbo Xu Paolo Galuppo Susanne Kneitz Manuel Mayr Georg Ertl Johann Bauersachs Thomas Thum

Journal: :Pharmacological reports : PR 2013
Anna Merwid-Ląd Małgorzata Trocha Ewa Chlebda-Sieragowska Tomasz Sozański Jan Magdalan Dorota Ksiądzyna Andrzej Szuba Maria Kopacz Anna Kuźniar Dorota Nowak Małgorzata Pieśniewska Lidia Fereniec-Gołębiewska Adam Szeląg

BACKGROUND The aim of the study was to evaluate the effect of cyclophosphamide (CPX) and morin-5'-sulfonic acid sodium salt (NaMSA) on plasma asymmetric dimethylarginine (ADMA) level and dimethylarginine dimethylaminohydrolase (DDAH) activity in rat liver. METHODS The study was performed on Wistar rats receiving normal saline, CPX (15 mg/kg/day), NaMSA (100 mg/kg/day) or both CPX and NaMSA fo...

Journal: :Analytical biochemistry 2010
Ted M Lakowski Cecilia Zurita-Lopez Steven G Clarke Adam Frankel

1 Abbreviations used: [methyl-C]AdoMet, S-adenosyl-L-[methyl-C]methionine; [methyl-H]AdoMet, S-adenosyl-L-[methyl-H]methionine; aDMA, asymmetric x-N,N-dimethylarginine; AdoMet, S-adenosyl-L-methionine; AdoHcy, S-adenosylL-homocysteine; CID, collision-induced dissociation; DMA, dimethylarginine; DTT, dithiothreitol; ESI, electrospray ionization; ETD, electron-transfer dissociation; FPLC, fast pe...

2005
Andrew J. Patterson Masumi Kimoto Helen M. Blau John P. Cooke Johannes Jacobi Karsten Sydow Georges von Degenfeld Ying Zhang Hayan Dayoub Bingyin Wang

Johannes Jacobi, Karsten Sydow, Georges von Degenfeld, Ying Zhang, Hayan Dayoub, Bingyin Asymmetric Dimethylarginine Levels and Enhances Angiogenesis Overexpression of Dimethylarginine Dimethylaminohydrolase Reduces Tissue Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2005 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Gree...

2017
You-Lin Tain Chien-Ning Hsu

Asymmetric and symmetric dimethylarginine (ADMA and SDMA, respectively) are toxic, non-proteinogenic amino acids formed by post-translational modification and are uremic toxins that inhibit nitric oxide (NO) production and play multifunctional roles in many human diseases. Both ADMA and SDMA have emerged as strong predictors of cardiovascular events and death in a range of illnesses. Major prog...

Journal: :Journal of the American College of Cardiology 2005
Thomas Thum Dimitrios Tsikas Sylvia Stein Maximilian Schultheiss Martin Eigenthaler Stefan D Anker Philip A Poole-Wilson Georg Ertl Johann Bauersachs

OBJECTIVES We tested the hypothesis that asymmetric dimethylarginine (ADMA) may be an endogenous inhibitor of endothelial progenitor cells (EPCs). BACKGROUND Endothelial progenitor cells play a pivotal role in regeneration of injured endothelium, thereby limiting the formation of atherosclerotic lesions. Reduced numbers of EPCs may affect progression of coronary artery disease. Regulation of ...

Journal: :Diabetes care 2007
Maciej T Malecki Anetta Undas Katarzyna Cyganek Barbara Mirkiewicz-Sieradzka Pawel Wolkow Grzegorz Osmenda Malgorzata Walus-Miarka Tomasz J Guzik Jacek Sieradzki

D ecreased availability of nitric oxide (NO), which contributes to the development of diabetes vascular complications (1), is partially related to asymmetric dimethylarginine (ADMA). ADMA is an endogenous NO synthase inhibitor (2) and a competitive inhibitor of cellular L-arginine uptake (3). ADMA has been associated with atherosclerosis in nondiabetic populations (4) and with diabetic nephropa...

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