the goal is assessing the diffusion magnetic resonance imaging (dmri) method effi ciency in characterizing focal hepatic lesions (fhls). about 28-fhl patients were studied in radiology and clinical imaging department of our university hospital using 1.5 tesla mri system between january 2010 and june 2011. patients underwent hepatic mri consisting of dynamic t1- and t2-weighted imaging. the dmri...

Background: Gliomas are the most common primary neoplasms of the central nervous system. Relative cerebral blood volume (rCBV) could estimate high-grade Gliomas computed with dynamic susceptibility contrast MR imaging which it is artificially lowered by contrast extravasation through a disrupted blood-brain barrier. Objectives: Our intent was to clarify the usefulness of diffusion-weighted m...

The four stereoisomers of azetidine-2,3-dicaroxylic acid (L-trans-ADC, L-cis-ADC, D-trans-ADC, and D-cis-ADC) were synthesized in a stereocontrolled fashion following two distinct strategies: one providing the two cis-ADC enantiomers and one giving access to the two trans-ADC enantiomers. The four azetidinic amino acids were characterized in a radioligand binding assay ([(3)H]CGP39653) at nativ...

BACKGROUND AND OBJECTIVE To prospectively investigate the relationship between the apparent diffusion coefficient (ADC) and cellularity in lung cancer. METHODS Sixty patients histopathologically confirmed with lung cancer (41 men, 19 women) underwent diffusion-weighted magnetic resonance imaging of the chest (with b values of 50 and 1000 s/mm2). The median mean ADC (ADC mean) value and median...

Variations in apparent diffusion coefficient of water (ADC) and blood-brain barrier (BBB) permeability after ischemia have been suggested, though the correlation between ADC alterations and BBB opening remains to be studied. We hypothesized that there are correlations between the alteration of ADC and BBB permeability. Rats were subjected to 2 h of transient middle cerebral artery occlusion and...

BACKGROUND AND PURPOSE A mismatch between diffusion- and perfusion-weighted MRI is thought to define tissue at risk of infarction. This concept is based on the assumption that diffusion slowing of and decreases in the apparent diffusion coefficient (ADC) serve as indicator of tissue proceeding to infarction. We tested this hypothesis. METHODS MRI (diffusion weighted, perfusion weighted, MRA, ...

BACKGROUND We tested the feasibility of a simple method for assessment of prostate cancer (PCa) aggressiveness using diffusion-weighted magnetic resonance imaging (MRI) to calculate apparent diffusion coefficient (ADC) ratios between prostate cancer and healthy prostatic tissue. METHODS The requirement for institutional review board approval was waived. A set of 20 standardized core transperi...

OBJECTIVE To investigate the utility of apparent diffusion coefficient (ADC) measurement in the diagnosis of chronic viral hepatitis (CVH) and correlation between ADC values and histopathologic severity of CVH. MATERIALS AND METHODS The ADC values of liver parenchyma on diffusion-weighted magnetic resonance imaging (DWMRI) were measured in 50 patients with a history of CVH and 51 healthy subj...

Four techniques for digital background calibration of SAR ADC are presented and compared. Sub-binary redundancy is the key to the realization of these techniques. Some experimental and simulation results are covered to support the effectiveness of these techniques. Keywords—SAR ADC, digital background calibration, DAC mismatch, bit weight, sub-binary redundancy

In this paper, Threshold Inverter Quantizer (TIQ) is a novel idea which can effectively replace the reference voltage generator, resistive/capacitive divider network and array of differential comparators in conventional flash Analog to Digital Converter (ADC) by an internal comparator constructed Complementary Metal Oxide Semiconductor (CMOS) inverters. The inverter threshold serving as voltage...