Exposing rats to a single session of inescapable tail shock (IS) reduces corticosteroid binding globulin (CBG) 24 h later (Fleshner et al., Endocrinology 136: 5336-5342, 1995). The present experiments examined whether reductions in CBG are differentially affected by controllable vs. identical uncontrollable tail shock, are mediated by IS-induced glucocorticoid elevation, or reflect IS-induced a...

There is a considerably high prevalence of vitamin D deficiency in patients with various disorders of the digestive system, including cystic fibrosis, acute and chronic pancreatitis, celiac disease, short bowel syndrome and inflammatory bowel disease. There are different causes of the vitamin D deficiency, and accordingly, there are different strategies for normalization of the vitamin D status...

C-reactive protein is the prototypic acute phase reactant. A self-complexed form (H-CRP) can induce isolated platelets to undergo aggregation, secretion of dense and alpha-granule constituents, and generation of thromboxane A2, but fails to function in platelet-rich plasma (PRP) as a direct agonist. In contrast, when PRP was activated with an amount of adenosine diphosphate (ADP) that produced ...

statement of problem: periodontal disease (pd) has been linked to adverse cardiovascular events by unknown mechanisms. c-reactive protein (crp) is a prognostic marker for cardiovascular disease, with reported elevated serum levels during pd. purpose: the aim of the present study was to evaluate the association between pd and higher crp levels in the serum of acute myocardial infarction (ami) pa...

Title:How age and sex affect the erythrocyte sedimentation rate and C-reactive protein in early rheumatoid arthritis. This study attempts to determine the impact of age, gender and BMI on the erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) in early rheumatoid arthritis. The findings are of interest but such studies are challenging to perform well given all of the potential conf...

OBJECTIVE To test new platelet indices for patients with rheumatoid arthritis (RA) as new acute phase reactants. MATERIAL AND METHODS In total, 120 patients with RA and 40 patients in the control group were analyzed. A DAS 28 score over 2.6 was accepted as active disease, and a DAS 28 score lower than 2.6 was accepted as under remission. Platelet distribution width, plateletcrit, and mean pla...

Transthyretin (TTR) is a serum protein which is a negative acute phase reactant in humans and levels of TTR are routinely measured as an indicator of health status. Such tests have yet to be established for the pig. In order to measure serum TTR in the pig during an acute phase response an assay was developed using anti-human TTR antibodies which cross reacted with porcine TTR. The assay had a ...