FACTORS EFFECTIVE IN THE PROGNOSIS OF NEUTROPENIC FEVER CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA

BACKGROUND Until recently, few molecular aberrations were recognized in acute lymphoblastic leukemia of T-cell origin; novel lesions have recently been identified and a certain degree of overlap between acute myeloid leukemia and T-cell acute lymphoblastic leukemia has been suggested. To identify novel T-cell acute lymphoblastic leukemia entities, gene expression profiling was performed and cli...

abstract background: high temperatures have destructive effects on cancer cells by damaging proteins and structures within cells. gold nanoparticles (aunps) can act as drug delivery vehicles, especially for cancer therapy. due to the selective intake of asparagine molecules into malignant cells, aunps were coated with asparagine; and ccrf-cem human t-cell leukemia cells were treated with the ne...

abstract background cancer diagnosis may cause deep emotional and affective problems in patients and their families.nowadays, however, despite its rising prevalence,cancer is no longer synonymous with death. given the significance of emotional well-being in cancer patients, we decided to assess the frequency of psychological problems in seven to seventeen yearolds with acute lymphoblastic leuke...

the appendix is an unusual site for extramedulary relapse in acute leukemia. the present case report describes two cases of late course acute lymphoblastic leukemia presented with leukemic infiltration of the appendix and complete remission of bone marrow. the signs and symptoms of the cases suggest that leukemic involvement of the appendix should be considered in the differential diagnosis of ...

NUDT15 genetic variants and 6-mercaptopurine intolerance in pediatric acute lymphoblastic leukemia: an updated review

unilateral malignant pleural effusion as an initial manifestation that leads to the diagnosis of an underlying acute lymphoblastic leukemia is a rare event. early and accurate diagnosis of this case is important for prompt and adequate therapy. we present the case of an18-year-old male who presented to the emergency department with severe respiratory distress. chest x-ray revealed a unilateral ...