background: idiopathic thrombocytopenic purpura (itp) is a chronic disease which is accompanied with hopelessness and loss of the sense of well-being due to its symptoms and treatment. it also affects patients' sense of social and spiritual well-being. this disorder decreases patients' self-esteem and their quality of life by changing their mental image and self-confidence. this study was perfo...

1 Feusner JH, Slichter SJ, Harker LA. Mechanisms of thrombocytopenia in varicella. Am J Hematol 1979;7: 255-64. 2 Espinoza G, Kuhn C, Viral infection of megakaryocytes in varicella with purpura. Am J Clin Pathol 1974;61:203-8. 3 Winiarski J. IgG and IgM antibodies to platelet membrane glycoprotein antigens in acute childhood idiopathic thrombocytopenic purpura. BrJ Haematol 1989;73:88-92. 4 Win...

Intracranial haemorrhage (ICH), a rare complication of idiopathic thrombocytopenic purpura (ITP), described only once previously in an adult, is usually fatal. We report a previously healthy 26 year old woman with chronic ITP in whom spontaneous ICH developed. The eventual favourable outcome in this case despite severe initial neurological deficit makes this case unusual. The importance of aggr...

Background: Eltrombopag is an orally bioavailable small molecule agonist of thrombopoietin receptor (TPO-R) that has been recently approved in the USA for treatment of chronic idiopathic (immune) thrombocytopenic purpura (ITP). The population pharmacokinetics of eltrombopag in healthy volunteers and patients with ITP has been previously described [1]. The model identified health status (healthy...

Metastatic duodenal adenocarcinoma is a rare disease, and it’s coexistence with idiopathic thrombocytopenic purpura is still very rare. Here we report first case of metastatic duodenal adenocarcinoma with coexistent ITP treated with palliative chemotherapy protocols. We initially managed ITP, after which having had a safe platelet count (above 75000/uL.), we safely administered chemotherapy pro...

Acute myocardial infarction (AMI) in patients with immune thrombocytopenic purpura (ITP) is rare. We describe a case of AMI in patient with ITP. An 81-year-old woman presented with acute inferoposterior MI with low platelet count on admission (34,000/µl). Coronary angiography revealed significant mid right coronary artery (RCA) stenosis with thrombus, subsequently underwent successful percutane...

Individual reprints of this article are not available. Address correspondence to Roberto Stasi, MD, Department of Medical Sciences, “Regina Apostolorum” Hospital, Via S. Francesco, 50, 00041 Albano Laziale, Italy (e-mail: [email protected]). ITP = immune thrombocytopenic purpura; IVIg = intravenous immunoglobulin Primary immune thrombocytopenic purpura (ITP), also referred to as idiopathi...

We thank Maquet et al 1 for their interest on our article entitled ‘Increased risk of systemic lupus erythematosus (SLE) in patients with autoimmune haemolytic anaemia (AIHA): a nationwide population-based cohort study’2 and the by Zhu 3 ‘Risk idiopathic thrombocytopenic purpura (ITP): study’. The articles us2 studied Taiwanese National Health Insurance Database reported that AIHA ITP have high...

Background and Objective: Different studies have investigated the link between helicobacter pylori and extra digestive diseases such as idiopathic thrombocytopenic purpura. However, the relationship between ITP and H pylori is less clear. Most of the studies have focused on H pylori eradication in chronic ITP, so we focused on the effect of H pylori eradication on chronicity of ITP in adult pat...