BACKGROUND Inhaled corticosteroids have dose related systemic effects determined by oral (swallowed or oropharyngeal absorption) and lung bioavailability. A study was undertaken to evaluate the significance of oropharyngeal absorption for fluticasone propionate. METHODS Sixteen healthy volunteers of mean age 29.3 years were studied using an open randomised, placebo controlled, four way crosso...

OBJECTIVE To inspect cigarettes with a triple granular filter for charcoal granules on the cut filter surface and, if present, to determine whether the charcoal granules on the filter are released during smoking. DESIGN 400 Lark cigarettes in 20 packs were examined individually by each of three investigators for the presence of charcoal granules on the cut surface of the cellulose acetate fil...

Recurrence of differentiated thyroid cancer can often require further surgical options. Reoperations may carry significant risk of surgical complications; additionally, as the anatomy is subverted, there is the possibility of leaving residual neoplasm. In order to avoid such problems during reoperation for differentiated thyroid cancer recurrence, we have introduced the technique of preoperativ...

A total of 280 unsexed broiler chicks, 21 days-old and weighing 580 g on average were randomly distributed into 28 experimental units of 10 birds each. Seven experimental diets containing respectively 0% (T0 control), 20% raw cowpeas (T1), 20% raw cowpeas + 0.2% of Canarium charcoal (T2), 20% raw cowpeas + 0.2% maize cob charcoal (T3), 20% cooked cowpeas (T4), 20% cooked cowpeas + 0.2% Canarium...

Single-dose activated charcoal therapy involves the oral administration or instillation by nasogastric tube of an aqueous preparation of activated charcoal after the ingestion of a poison. Volunteer studies demonstrate that the effectiveness of activated charcoal decreases with time. Data using at least 50 g of activated charcoal, showed a mean reduction in absorption of 47.3%, 40.07%, 16.5% an...

African woodlands form a major part of the tropical grassy biome and support the livelihoods of millions of rural and urban people. Charcoal production in particular is a major economic activity, but its impact on other ecosystem services is little studied. To address this, our study collected biophysical and social datasets, which were combined in ecological production functions, to assess eco...