A mutant of Cephalosporium acremonium producing high amounts of penicillin N was isolated. This antibiotic was purified and characterized. It was possible to convert this penicillin N to deacetoxycephalosporin C enzymatically. The reaction could be carried out with enzyme systems prepared from C. acremonium mutants producing either no S-lactam antibiotics or excreting only penicillin N. It was ...

Primarily saprophytic in nature, fungi of the genus Acremonium are a well-documented cause of mycetoma and other focal diseases. More recently, a number of Acremonium spp. have been implicated in invasive infections in the setting of severe immunosuppression. During the course of routine microbiological studies involving a case of fatal mycosis in a nonmyeloablative hematopoietic stem cell tran...

Penelitian ini bertujuan untuk mengetahui genus kapang yang berpotensi menyebabkan kerusakan serta jenis biodeteriorasi terjadi pada batuan Candi Mendut. Jenis penelitian digunakan dalam adalah deskriptif kualitatif. diawali dengan survey sampling dilakukan berdasarkan syarat : kenampakan miselium, spora, bercak warna, dan substrat. Identifikasi secara konvensional pengamatan makroskopik mikros...

The title compound, C(13)H(16)O(4), was isolated from culture extracts of the endophytic fungus Cephalosporium sp. The ester and ether substituents are twisted only slightly out of the benzene ring plane, making dihedral angles of 2.16 (2) and 3.63 (5)°, respectively. The non-H atoms of all three substituents are almost coplanar with the benzene ring, with an r.m.s. deviation of 0.0284 Å from t...

Syngonium podophyllum Schott, commonly referred to as Nephthytis, in commercial chan nels ranks fourth in economic importance in the ornamental foliage industry of Florida and has a sales value of approximately $350,000 annu ally. Of the relatively few diseases which affect Syngonium, a leaf spot caused by Cephalospo rium dnnamomeum Linn has been observed to occur with not uncommon frequency an...

Plectosphaerella cucumerina, most frequently encountered in its Plectosporium state, is well known as a pathogen of several plant species causing fruit, root and collar rot, and collapse. It is considered to pose a serious threat to melon (Cucumis melo) production in Italy. In the present study, an intensive sampling of diseased cucurbits as well as tomato and bell pepper was done and the funga...

Wehave studied the microbial transformation of griseofulvin (I) by Cephalosporium curtipes and the formation of two more polar metabolites was observed in a proportion of 10:1. The compounds have been identified as (+)-5'-hydroxygriseofulvin (axial) (II) and G'-hydroxymethylgriseofulvin (III) (Fig. 1). The microbial transformation of griseofulvin was performed by a 48-hour-old culture of Cephal...

Cephalosporin C (CPC), a β-lactam antibiotic, is starting molecule for industrial production of semi synthetic cephalosporins. CPC fermentation has been carried out in Air Lift Reactor (indigenously made up of borosilicate glass) in different fermentation modes i.e., batch and fed batch modes using a mold Acremonium chrysogenum (synn. Cephalosporium acremonium). A definite correlation exists be...

This report describes two cases of Acremonium sp. endophthalmitis, occurring in two patients who underwent cataract surgery on the same day in the same operating room of our hospital ophthalmology clinic. Diagnosis of fungal endophthalmitis was established by the repeated isolation of the same fungal agent from vitreous washing, acqueous fluid and intraocular lens samples and by its identificat...