Benzynes react with allylic acetates or halides and terminal alkynes in the presence of Pd(PPh3)4, CuI and CsF in CH3CN at 50 degrees C for 5 h to give 1-allyl-2-alkynylbenzene derivatives in good to excellent yields.

A copper-mediated trifluoromethylation of propargyl acetates with S-(trifluoromethyl)diphenylsulfonium triflate leading to trifluoromethylated allenes in moderate to excellent yields is described.

An N-heterocyclic carbene catalyzed enantioselective [3+3] annulation of benzothiazolyl acetates with 2-bromoenals has been developed. The protocol provides a direct asymmetric synthesis of dihydro-1H-benzothiazolopyridinones in good to very good yields and medium ee values. In many cases, the virtually enantiopure heterocycles are available through a single recrystallization (99% ee).

Cellulose acetate fibers are commonly made by a dry-spinning process, in which cellulose acetate is firstly dissolved in acetone and then the cellulose acetate acetone solution is extruded through spinneret orifices that have extremely small diameters. Any insoluble substances in acetone solutions could cause disruptions in fiber extrusion, and are not tolerated. In this work, acetone-insoluble...

The mechanisms of gold(III)-catalyzed synthesis of highly substituted furans via [3,3]-sigmatropic rearrangements and/or [1,2]-acyloxy migration based on propargyl ketones have been investigated using density functional theory calculations at BHandHLYP/6-31G(d,p) (SDD for Au) level of theory. Solvent effects on these reactions were explored using calculations that included a polarizable continu...

This study measured the impact of alisol B 23-acetate and alisol A 24-acetate, the main active ingredients of the traditional Chinese medicine Alismatis rhizoma, on total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), and low density lipoprotein-cholesterol (LDL-C) levels of hyperlipidemic mice. The binding of alisol B 23-acetate and alisol A 24-acetate to th...

A series of ethyl 2-[2-arylamino-4-(thiophen-2-yl)thiazol-5-yl] acetates (5a-5k) and ethyl 2-[2-(arylhydrazino)-4-(thiophen-2-yl)thiazol-5-yl] acetates (9a-9g) were synthesized and screened for their anti-inflammatory, analgesic, and antioxidant activities. In vivo test results showed that the compounds with halogen substitution (5c, 5g, 5h, 5i and 5j) at the para position on the 2-aryl amino g...

A combination of IPrAuNTf(2) as catalyst in the presence of Selectfluor has been successfully used for the high yielding synthesis of α-fluoroenones via 1,3-acyloxy rearrangement of propargyl acetates followed by Csp(2)-F bond formation, likely involving a redox Au(I)/Au(III) catalytic cycle.

Using enantioselective M D G C the enantiom eric d istribution o f alkan-(alken-)2-yl-acetates from bananas is achieved. A fter simple acetylation their corresponding alcohols 2-pentanol, 2-hexanol, 2-heptanol and (Z)-4-hepten-2-ol respectively are also exactly stereodifferentiated by the same method. All com pounds investigated esters as well as alcohols exhibit a rem arkable excess o f the (5...