Alternating doses of ibuprofen and acetaminophen provided an effective treatment for post-tonsillectomy pain in the majority of children and did not increase rate of bleeding.The new finding appear in Annals of Otology, Rhinology & Laryngology. Pain control after tonsillectomy in children is critical for a good quality of postoperative recovery. Opioids, acetaminophen and non steroidal anti-inf...

UNLABELLED We enrolled 120 children undergoing bilateral myringotomy and tube placement in this prospective, randomized, observer-blinded study. Patients were randomized into one of four groups: Group 1 (control) was plain acetaminophen 10 mg/kg orally, Group 2 was acetaminophen 10 mg/kg with 1 mg/kg of codeine orally, Group 3 was transnasal butorphanol 25 micro g/kg given immediately after the...

OBJECTIVE To assess the effect of the UK Committee on Safety of Medicines' announcement in January 2005 of withdrawal of co-proxamol on analgesic prescribing and poisoning mortality. DESIGN Interrupted time series analysis for 1998-2007. SETTING England and Wales. DATA SOURCES Prescribing data from the prescription statistics department of the Information Centre for Health and Social Care...

OBJECTIVE To determine the effect of ibuprofen on posttonsillectomy bleeding when compared with codeine in posttonsillectomy analgesia. STUDY DESIGN Case series with chart review. SETTING Tertiary care children's hospital, Philadelphia, Pennsylvania. SUBJECTS AND METHODS On July 1, 2012, our institution transitioned from acetaminophen with codeine to ibuprofen for posttonsillectomy analge...

The study aims to provide an updated assessment of the evidence for individual pharmacological therapies for acute migraine treatment. Pharmacological therapy is frequently required for acutely treating migraine attacks. The American Academy of Neurology Guidelines published in 2000 summarized the available evidence relating to the efficacy of acute migraine medications. This review, conducted ...

The purpose of this prospective, randomized, blinded study was to determine the effect of apical trephination on postoperative pain and swelling in symptomatic necrotic teeth. Fifty emergency patients participated, and each had a clinical diagnosis of a symptomatic necrotic tooth with associated periapical radiolucency. After endodontic treatment, patients randomly received either an apical tre...

CLINICAL HISTORY Thirty minutes after sexual intercourse, this 48-year-old woman noticed a slight headache on the top of her head. Fifteen minutes later, she developed a severe left-sided throbbing headache with visual symptoms but without nausea, light, or noise sensitivity. She had a sudden warm liquid feeling in the left eye and then vision in the inferior field of the left eye became dark a...

INTRODUCTION Acute periradicular abscess is a condition characterized by the formation and propagation of pus in the periapical tissues and generally associated with debilitating pain. OBJECTIVE The aim of this study was to compare the overall analgesic effectiveness of two combinations of opioid and non-opioid analgesics for acute periradicular abscess. MATERIAL AND METHODS This study incl...