objective: this study determined the chromosomal constitution of recurrent spontaneous abortions by comparative genomic hybridization (cgh) analysis of fetal samples. material and methods:   forty pregnant women with early recurrent pregnancy losses aged 21 to 42 years old from tehran university of medical sciences affiliated hospitals entered in this descriptive study. hibridization analysis o...

introduction: the purpose of the screening of fetal anomalies in pregnancy is empowering women to make an informed choice and reduce uncertainty in decision making. on the other hand, screening may cause worry and anxiety in pregnant women. this study was conducted with aim to determine the relationship between informed choice in pregnant women about screening of fetal anomalies with worry and ...

cornelia de lange syndrome (cdls) is a rare syndrome characterized by multiple congenital anomalies, mental retardation, characteristic facial appearance, developmental delay, skeletal malformation, hirsutism, and various cardiac and ophthalmological problems. the diagnosis of this syndrome is clinical. the patient of the present case report was the second case of cdls from iran ; only a few ca...

inroduction: heart failure (hf) is an important cause of morbidity and mortality in the cases of beta-thalassemia major. the purpose of this study was to estimate hf prevalence in these patients and to assess the survivability of those who were treated with intensive chelating therapy.   design and methods: this cross sectional study included 72 beta-thalassemia major cases, the mean age at the...

introduction:patients with cyanotic heart disease may have an acceptable quality of life. however, they are invariably prone to several complications. the aim of this study is search about hematologic abnormalities in cyanotic congenital heart disease patients. materials and methods:  in this cross sectional study every cyanotic congenital heart disease patients who was referred to the adult co...

background:cardiovascular effects of acute organophosphate (op) poisoning are common. this study was aimed to assess the cardiovascular effects of op poisoned patients in nepal. methods:this was a prospective hospital-based cross-sectional study of 115 acute op poisoned patients presenting in emergency department of a tertiary care teaching hospital of central nepal during november 2008 to octo...

to study the effect of depression on the endocrine and immune systems, 557 male freshman and sophomore medical students (20-30 years old) were given beck's depression inventory. students with marks 5 or above were selected as the control (n=26) and those with marks of 20 or higher were chosen as the test group (n=27). all of the students were subjected to the following tests: cbc, differen...

root canal anatomy diversity and aberrations are common especially in permanent dentition. a thorough understanding of the basic root canal anatomy and its diversities are necessary for successful endodontic treatment. mandibular second premolars are usually single-rooted and have one root canal. incidence of three separate root canals in this tooth is quite rare and taurodontism with three sep...

objective proteus syndrome is an extremely rare, sporadic and progressive disorder. we describe a four-month-old male baby with central nervous system manifestations in this article. clinical presentation a four-month-old boy was admitted into our hospital with three tonic - clonic generalized seizure attacks which started from the day before admission. each seizure attack lasted less than 10 m...

objective(s) carbamazepine (cbz) is an antiepileptic drug that is used widely for the treatment of epileptic seizures. neural tube defects (ntds), growth retardation, and nail hypoplasia are the most common features of teratogenic effects of this drug. the purpose of this study was to examine the effect of vitamin b6 on the developmental toxicity of cbz on mice. materials and methods sixty balb...