Introduction The bond strength of the resinmetal interface of a prosthesis is a key factor in determining the serviceability of that prosthesis. Separation of the resin from the metal due to a compromised or weak bond can lead to microleakage, discoloration and total separation of the resin from the metal.1,2 Resin-metal bonding systems as an addition to or replacement for conventional mechanic...

OBJECTIVE Although iron is an essential element for maintaining physiological function, excess iron leads to tissue damage caused by oxidative stress and inflammation. Oxidative stress and inflammation play critical roles for the development of abdominal aortic aneurysm (AAA). However, it has not been investigated whether iron plays a role in AAA formation through oxidative stress and inflammat...

OBJECTIVE To identify proteins related to intraluminal thrombus biological activities that could help to find novel pathological mechanisms and therapeutic targets for human abdominal aortic aneurysm (AAA). APPROACH AND RESULTS Tissue-conditioned media from patients with AAA were analyzed by a mass spectrometry-based strategy using liquid chromatography coupled to tandem mass spectrometry. Gl...

BACKGROUND Screening for abdominal aortic aneurysm (AAA) is known to reduce AAA-related mortality; however, the psychological impact of population AAA screening is unclear. The aim was to assess the impact of AAA diagnosis on quality of life (QoL) using data from an established AAA screening programme. METHODS Mental and physical QoL scores for men diagnosed with AAA through participation in ...

PURPOSE/OBJECTIVES To examine the perceptions of staff members toward the implementation of an animal-assisted activity (AAA) in an outpatient regional cancer center. DESIGN Quasi-experimental, post-test design. SETTING An adult outpatient regional cancer center in northern California. SAMPLE 34 facility staff members. METHODS Self-report questionnaire following four weeks of AAA visita...

Background—Obesity is associated with occlusive artery disease but is not considered a risk factor for abdominal aortic aneurysm (AAA). We investigated the association between anthropometric measures of obesity, serum adipokines, and AAA. Methods and Results—As part of a population study, we screened 12 203 men 65 to 83 years of age for AAA using ultrasound; 875 had an AAA ( 30 mm). Cardiovascu...

OBJECTIVE Polymorphonuclear neutrophils (PMNs) play a main role in abdominal aortic aneurysm (AAA) progression. We have analyzed circulating PMNs isolated from AAA patients and controls by a proteomic approach to identify proteins potentially involved in AAA pathogenesis. METHODS AND RESULTS PMNs from 8 AAA patients (4 large AAA >5 cm and 4 small AAA 3-5 cm) and 4 controls were analyzed by 2D...

BACKGROUND Obesity is associated with occlusive artery disease but is not considered a risk factor for abdominal aortic aneurysm (AAA). We investigated the association between anthropometric measures of obesity, serum adipokines, and AAA. METHODS AND RESULTS As part of a population study, we screened 12,203 men 65 to 83 years of age for AAA using ultrasound; 875 had an AAA (> or = 30 mm). Car...

BACKGROUND Mast cell chymase may participate in the pathogenesis of human abdominal aortic aneurysm (AAA), yet a direct contribution of this serine protease to AAA formation remains unknown. METHODS AND RESULTS Human AAA lesions had high numbers of chymase-immunoreactive mast cells. Serum chymase level correlated with AAA growth rate (P=0.009) in a prospective clinical study. In experimental ...

Abdominal aortic aneurysm (AAA) is very frequently accompanied by coronary artery disease. Myocardial ischemia is the leading cause of mortality and morbidity in AAA repair. Therapeutic strategy, in presence of ischemic heart failure and AAA, is not well established. Actually, AAA is considered as a contraindication to ventricular assist device (VAD) support. We report a unique case of concomit...