In myelodysplastic syndrome (MDS), the expression of the cyclin-dependent kinase inhibitor p15ink4B (p15) is frequently decreased because of the aberrant methylation of the gene promoter; p15 is normally up-regulated during megakaryocytic differentiation. It was hypothesized that p15 methylation and deregulation of gene expression contribute to defective megakaryocytopoiesis in patients with MD...

OBJECTIVE: To describe the sampling plan and estimation methods used to collect and analyze data in the survey Sexual Behavior and Perceptions of the Brazilian Population concerning HIV/Aids in 2005. METHODS: The study presents the decisions that were made concerning population defi nition, strata of interest to the survey and to the sampling plan, main procedures for data analysis and sample p...

We explored the use of multidimensional scaling (MDS) of tree-to-tree pairwise distances to visualize the relationships among sets of phylogenetic trees. We found the technique to be useful for exploring "tree islands" (sets of topologically related trees among larger sets of near-optimal trees), for comparing sets of trees obtained from bootstrapping and Bayesian sampling, for comparing trees ...

In this paper a new sequential sampling plan is introduced in which the acceptable quality level (AQL) and the lot tolerance percent defective (LTPD) are a fuzzy number. This plan is well defined, since, if the parameters are crisp, it changes to a classical plan. For such a plan, a particular table of rejection and acceptance is calculated and compared with the classical one. Keywords : St...