1Okinawa International University, Okinawa 901-2701, Japan 2Okinawa Research Center for Longevity Science, Okinawa 901-2114, Japan 3Pacific Health Research and Education Institute, Honolulu, HI 96813, USA 4Department of Research, Kuakini Medical Center, Honolulu, HI 96817, USA 5Department of Research, Planning and Development, The Queen’s Medical Center, Honolulu, HI 96813, USA 6Department of G...

901 ©2011 Society For Biomaterials

Juliana Barbosa Saliba, Armando da Silva Cunha Junior e Elionai Cassiana de Lima Gomes Faculdade de Farmácia, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627, 31270-901 Belo Horizonte MG, Brasil Herman Sander Mansur Departamento de Engenharia Metalúrgica e de Materiais, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627, 31270-901 Belo Horizonte MG, Brasil...

J. R. De Long (orcid.org/0000-0002-7951-4818)([email protected]), P. Kardol, M. K. Sundqvist, G. F. Veen and D. A. Wardle, Dept of Forest Ecology and Management, Swedish Univ. of Agricultural Sciences, SE-901 83, Ume å , Sweden. MKS also at: Dept of Ecology and Environmental Science, Ume å Univ., SE-901 87, Ume å Sweden. GFV also at: Dept of Terrestrial Ecology, Netherlands Inst. of Ecolo...

The serine-threonine kinase CK2 exhibits genomic alterations and aberrant overexpression in human head and neck squamous cell carcinomas (HNSCC). Here, we investigated the effects of CK2 inhibitor CX-4945 in human HNSCC cell lines and xenograft models. The IC50's of CX-4945 for 9 UM-SCC cell lines measured by MTT assay ranged from 3.4-11.9 μM. CX-4945 induced cell cycle arrest and cell death me...

BACKGROUND The activation of the MAPK and PI3K/AKT/mTOR pathways is implicated in the majority of cancers. Activating mutations in both of these pathways has been described in colorectal cancer (CRC), thus indicating their potential as therapeutic targets. This study evaluated the combination of a PI3K/mTOR inhibitor (PF-04691502/PF-502) in combination with a MEK inhibitor (PD-0325901/PD-901) i...

A. Talarmin, F. Van Wambeke, P. Catala, C. Courties, and P. Lebaron Université de la Méditerranée – Aix Marseille 2, UMR 6117, Centre d’Océanologie de Marseille, Case 901, Campus de Luminy, 13288 Marseille, France CNRS/INSU, UMR 6117, LMGEM, Case 901, Campus de Luminy, 13288 Marseille, France UPMC Univ Paris 06, Laboratoire ARAGO – Observatoire Océanologique, 66651 Banyuls/mer, France CNRS, UMR...

Henriete S. Vieira, Jacqueline A. Takahashi, Alaíde B. de Oliveira, Egler Chiari and Maria Amélia D. Boaventura* Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, 31270-901, Belo Horizonte MG, Brazil Departamento de Produtos Farmacêuticos, Faculdade de Farmácia , Universidade Federal de Minas Gerais, Av. Olegário Maciel, 2360,...

A crystalline material with a two-dimensional structure, termed metal-organic framework-901 (MOF-901), was prepared using a strategy that combines the chemistry of MOFs and covalent-organic frameworks (COFs). This strategy involves in situ generation of an amine-functionalized titanium oxo cluster, Ti6O6(OCH3)6(AB)6 (AB = 4-aminobenzoate), which was linked with benzene-1,4-dialdehyde using imin...

Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that occur spontaneously, or from benign plexiform neurofibromas, in the context of the genetic disorder Neurofibromatosis Type 1 (NF1). The current standard treatment includes surgical resection, high-dose chemotherapy, and/or radiation. To date, most targeted therapies have failed to demonstrate effectiveness against p...