From the ‡Institute for Health Sciences, Tokushima Bunri University, 180 Nishihama-bouji, Yamashiro-cho, Tokushima 770-8514, Japan, the **Department of Biological Sciences and Technology, Faculty of Engineering, the University of Tokushima, 2-1 Minamijosanjimacho, Tokushima 770-8506, Japan, the ‡‡Structural Biophysics Laboratory, RIKEN Harima Institute at SPring-8, 1-1-1 Kouto, Mikazuki, Sayo, ...

MLK3 is a serine/threonine protein kinase that functions as an upstream activator of the JNK pathway. Previous work has suggested that MLK3 is a multiphosphorylated protein. In this study, mass spectrometry coupled with comparative phosphopeptide mapping was used to directly characterize MLK3 in vivo phosphorylation sites. Various types of mass spectrometry were used to analyze MLK3 tryptic pep...

To identify the divalent metal ions that can support the self-cleavage activity of the genomic ribozyme of human hepatitis delta virus (HDV), we tested the activity of various divalent metal ions in the ribozyme reactions catalyzed by HDV88 (683-770 nt) and 88DI3 (HDV88 with the sequence from 740-752 nt deleted). Among various metal ions tested, Mg2+, Mn2+, Ca2+ and Sr2+ efficiently supported t...

AIM: We aimed to evaluate changes in patient numbers, procedures performed, and the result of imaging breast unit a non-pandemic hospital Turkey during COVID-19 pandemic.
 MATERIAL AND METHOD: The study retrospectively evaluated 2010 740 patients who presented our pandemic periods, respectively. Patient sex age, neoadjuvant chemotherapy story, modalities used, final BI-RADS classification,...

Introduction: leiomyoma is the most common benign esophageal neoplasm. Surgical treatment (enucleation) has traditionally been the therapy of choice. The advent of minimally invasive techniques has produced an increase in endoscopic approaches to the detriment of open surgery. Objective: the aim of this study was to compare the results obtained with open surgery and with laparoscopic surgery in...

1 Departamento de Ciências Farmacêuticas, Universidade Federal de Santa Catarina – UFSC, Florianópolis, SC, Brazil. 2 Departamento de Farmácia, Universidade Estadual de Ponta Grossa – UEPG, Ponta Grossa, PR, Brazil. 3 Departamento de Farmacologia, Universidade Federal de Santa Catarina – UFSC, Florianópolis, SC, Brazil. 4 Departamento de Ciências Farmacêuticas, Universidade do Vale do Itajaí – ...

transfer of patients from the cardiac intensive care unit to the general ward, is one of the main reasons for anxiety. given that the transfer anxiety may be due to receive at least, inconsistent or do not receive enough information before the patients leaving the intensive care unit, therefore, this study aimed to determine the effect of information provision on anxiety levels in patients tran...

Assays for blood levels of prostate-specific antigen (PSA), performed in prostate cancer detection, measure mostly inactive/complexed PSA and do not provide information regarding enzymatically active PSA, which is biologically more relevant. Thus, we designed and synthesized an enzymatically cleavable peptide sequence labeled with near-infrared (NIR) fluorophores (ex/em 740/770  nm) and coupled...

1Biochimie et Physiologie Moléculaire des Plantes, Unité Mixte de Recherche CNRS-INRA, Université Montpellier 2, Montpellier SupAgro, Place Viala, 34060 Montpellier, France 2Department of Botany, University of Jammu, Jammu , Jammu and Kashmir 180-006, India 3Jacob Blaustein Institute for Desert Research, BGU, 84990 Sede-Boqer Campus, Israel 4Department of Microbiology and Plant Biology, Univers...