Bladder herniation is an uncommon condition mimicking suspicious metastasis on PET/CT imaging. We report a 67 y/o man with prostate cancer referred for recurrence evaluation with 68Ga-PSMA-11 PET/CT. The scan showed an asymmetric site of intense tracer accumulation in the left inguino-scrotal region with the same SUVmax to the pelvic bladder. Reviewing cross sectional CT i...

Context: Gallium prostate-specific membrane antigen (PSMA) ligand Ga-HBED-CC-PSMA (Ga-PSMA) is a promising radiotracer for positron emission tomography (PET)/computed tomography (CT) of prostate cancer. Objective: To conduct a meta-analysis to evaluate detection rate, diagnostic test accuracy, and adverse effects of Ga-PSMA PET/CT or PET/magnetic resonance imaging (MRI) for staging of prostate ...

Objective Prostate-specific membrane antigen (PSMA) is a cell-surface protein widely expressed on most prostate cancer cells that has rapidly emerging clinical utility in the realm of cancer. This systematic review aims to evaluate efficacy as well cost-effectiveness PSMA roles diagnosis and treatment management. Background The use initial staging patients, early detection recurrence, response ...

In spite of the hazard due to the radiation exposure, preparation of 90Y- and 177Lu-labelled radiopharmaceuticals is still mainly performed using manual procedures. In the present study the performance of a commercial automatic synthesizer based on disposable cassettes for the labelling of 177Lu- and 90Y-DOTA-conjugated biomolecules (namely, DOTATOC and PSMA-617) was evaluated and compared to a...

Background: By targeting the prostate-specific membrane antigen (PSMA) on prostate cancer (PCa) cells PSMA-PET/CT shows great potential in locating the site of biochemical recurrence even at low PSA (Prostate-specific antigen)-levels. Accurate imaging of PCa recurrent lymph node metastases (LNM) is crucial for metastases directed therapies such as salvage-lymph node dissection (salvage-LND). Ob...

Mazur [8] has introduced the concept of visible elements in the Tate-Shafarevich group of optimal modular elliptic curves. We generalized the notion to arbitrary abelian subvarieties of abelian varieties and found, based on calculations that assume the BirchSwinnerton-Dyer conjecture, that there are elements of the Tate-Shafarevich group of certain sub-abelian varieties of J0(p) and J1(p) that ...

We classify the possible Mumford-Tate groups of polarizable rational Hodge structures.

We prove that for abelian varieties with semistable ordinary reduction the p-adic Mazur-Tate height pairing is induced by the unit root splitting of the Hodge filtration on the first deRham cohomology.

We improve Kolyvagin’s upper bound on the order of the p-primary part of the Shafarevich-Tate group of an elliptic curve of rank one over a quadratic imaginary field. In many cases, our bound is precisely the one predicted by the Birch and Swinnerton-Dyer conjectural formula.