نتایج جستجو برای: 635 سال
تعداد نتایج: 160441 فیلتر نتایج به سال:
The objective of the present study was to investigate whether pretreatment with single low loading dose of tongxinluo (TXL), a traditional Chinese medicine, 1 h before myocardial ischemia could attenuate no-reflow and ischemia-reperfusion injury by regulating endothelial nitric oxide synthase (eNOS) via the PKA pathway. In a 90-min ischemia and 3-h reperfusion model, minipigs were randomly assi...
We examined the influence of individual serine phosphorylation sites in endothelial nitric-oxide synthase (eNOS) on basal and stimulated NO release, cooperative phosphorylation, and co-association with hsp90 and Akt. Mutation of the serine phosphorylation sites 116, 617, and 1179 to alanines affected the phospho-state of at least one other site, demonstrating cooperation between multiple phosph...
O presente estudo objetiva uma análise do controle concentrado de constitucionalidade no Brasil em especial a Arguição Descumprimento Preceito Fundamental número 635, relatoria ministro Edson Fachin. A problemática trabalho consiste averiguar se supracitada ação, durante pandemia novo coronavírus, demonstra-se suficiente para proteger os direitos fundamentais da população residente áreas carent...
Abstract Case 48-year-old male presented for elective open recurrent right inguinal hernia (RIH) repair due to ongoing inguinoscrotal swelling; and an ultrasound suggestive of a large indirect containing peritoneal fat extending into the scrotum with displacement testis. Previous RIH mesh completed 12mths prior found moderate direct hernia; during post-op phone review (given COVID pandemic) not...
3-Hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors, statins, provide beneficial effects independent of their lipid-lowering effects. One beneficial effect appears to involve acute activation of endothelial nitric oxide (NO) synthase (eNOS) and increased NO release. However, the mechanism of acute statin-stimulated eNOS activation is unknown. Therefore, we hypothesized that eNOS activatio...
In evaluating the autofluorescence properties of normal and diseased skin we discovered that psoriatic plaques can emit a distinct red fluorescence when illuminated with UVA or blue light. Using a macrospectrofluorometer equipped with a 442 nm excitation laser, a sharp in vivo fluorescence emission peak around 635 nm could be demonstrated within the plaques of 34 of 75 (45%) patients with psori...
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