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BACKGROUND A few polymorphisms are located in the mature microRNA sequences. Such polymorphisms could directly affect the binding of microRNA to hundreds of target mRNAs. It remains unknown whether rs4919510:C>G located in the mature miR-608 alters breast cancer susceptibility. METHODS The association of rs4919510:C>G with risk and pathologic features of breast cancer were investigated in two...
BACKGROUND AND AIMS MicroRNAs (miRNAs) are known for their function as translational regulators of tumor suppressor or oncogenes. Single nucleotide polymorphisms (SNPs) in miRNAs related genes have been shown to affect the regulatory capacity of miRNAs and were linked with gastric cancer (GC) and premalignant gastric conditions. The purpose of this study was to evaluate potential associations b...
Anne-Christine Brehm, Netzwerk Gotik. Das Ulmer Münster im Zentrum von Architektur- und Bautechniktransfer (Forschungen zur Geschichte der Stadt Ulm 36). Stuttgart: Kohlhammer 2020. 608 S. ISBN 978-3-17-038135-3. € 59,–
0006-3207/$ see front matter Published by Elsevier Ltd. http://dx.doi.org/10.1016/j.biocon.2013.01.010 ⇑ Corresponding author. Tel.: +1 608 781 6309; fax: +1 608 783 6066. E-mail addresses: [email protected] (W.E. Thogmartin), [email protected] (C.A. Sanders-Reed), [email protected] (P.C. McKann), [email protected] (L. Pruitt), [email protected] (R.A. King), [email protected] (M.C. Runge), r...
A mathematically simple example of a high-dimensional (many-species) Lotka-Volterra model that exhibits spatiotemporal chaos in one spatial dimension is described. The model consists of a closed ring of identical agents, each competing for fixed finite resources with two of its four nearest neighbors. The model is prototypical of more complicated models in its quasiperiodic route to chaos (incl...
Background The serotonin transporter (SERT) belongs to the SLC6 family of neurotransmitter transporters, which mediate reuptake of previously released neurotransmitters from the synapse. Mutation of C-terminus residues RI607– 608 to alanine results in intracellular retention of SERT [1]. We subsequently showed that SERT depends on the COPII component SEC24C for its ER export and proposed RI607–...
researchers within the last few decades because of its great potential utility for rapid drug delivery. It offers an attractive alternative for drugs that have limited oral bioavailability, are destroyed by gastrointestinal (GI) fluid, or are highly susceptible to hepatic first pass or gut-wall metabolism. Nasal drug delivery also offers the convenience and safety of noninvasiveness. In additio...
Gerardo Sánchez Díaz, La presencia del exilio republicano español en la Universidad Michoacana (1938-1966), Madrid, de San Nicolás Hidalgo/Marcial Pons, 2020, 608 pp., cuadros, ils. (Historia Contemporánea América). ISBN: 978-84-1381-014-0
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