Supplementary Materials: The following are available online at http://www.mdpi.com/1999-4915/7/11/2919, Figure S1: DLS analysis of PV 3CD protein, Figure S2: PCA analysis reveal major motions of 3CD, Figure S3: MD simulations reveal multiple interfaces in WT and mutant 3CD, Figure S4: Mutations of 3CD in the crystal structure, Figure S5: Analysis of the 50 ns MD simulations of mutant PV 3CD, an...

ADVERTISEMENT RETURN TO ISSUEPREVEnergy FocusNEXTNGenE 2022: Electrochemistry for DecarbonizationJordi Cabana*Jordi CabanaDepartment of Chemistry, University Illinois at Chicago, 60607, United States*[email protected]More by Jordi Cabanahttps://orcid.org/0000-0002-2353-5986, Thomas AlaanThomas AlaanDepartment Physics, StatesMore Alaan, George W. CrabtreeGeorge CrabtreeDepartment StatesJoint Cen...

Understanding the factors that stabilize R-helices is critical to understanding protein folding.1 Structure and sequence information for naturally occurring proteins has revealed a preference for certain amino acids in R-helices.2 Thus, many studies have focused on the individual effects of the amino acids on R-helix stability,3,4 and algorithms have been developed that can predict helix conten...

The biodistribution of |l2SI]iododihydrorhodamine 123 has been studied over a 96-h period in four human tumor xenograft models: HT-29 colon adenocarcinoma, PC-3 prostate carcinoma, HT-1080 fibrosarcoma, and PaCa-2 pancreatic carcinoma. Elimination of radioactivity in the tumorbearing nude mice was rapid during the first 24 h and slow thereafter. The lack of uptake in the thyroid indicated there...